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BioWorld - Wednesday, May 6, 2026
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Respiratory

Chiesi Farmaceutici defines ALK5 inhibitors for idiopathic pulmonary fibrosis

Aug. 8, 2023
Chiesi Farmaceutici SpA has patented TGF-β receptor type-1 (ALK5) inhibitors reported to be useful for the treatment of idiopathic pulmonary fibrosis.
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FDA breathes life into Etiometry’s algorithm for neonatal hypercapnia risk

Aug. 3, 2023
By Meg Bryant
Premature babies face challenges in the neonatal intensive care unit (NICU) as their heart, lungs and neurological system continue to develop outside the womb. Roughly half of neonates born at 26 weeks to 28 weeks gestation experience respiratory distress. These infants often need extra oxygen and help breathing, as well as constant monitoring to ensure oxygen is absorbed and carbon dioxide (CO2) is dispelled. To that end, Etiometry Inc. received FDA clearance for its IVCO2 Index, a software tool for use in monitoring risk of hypercapnia in NICU patients weighing less than 2 kg.
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Respiratory

NO donors identified in Guangzhou Kaishi Pharma patent

Aug. 2, 2023
Guangzhou Kaishi Pharmaceutical Co. Ltd. has patented treprostinil derivatives acting as nitric oxide (NO) donors reported to be useful for the treatment of acute respiratory distress syndrome, pulmonary arterial hypertension and arterial occlusion.
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Lungs wireframe illustration

Developers selectin’ galectin across range of indications

July 31, 2023
By Randy Osborne
The notion of taking aim at the galectin pathway across varied therapeutic areas has gained major traction in recent years, with a handful of companies drawing Wall Street’s interest as efforts plow forth in conditions as varied as cancer, liver fibrosis and Alzheimer’s disease.
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Hyfe AI-driven remote patient monitoring program (RPM)

Hyfe touts AI-driven RPM program for monitoring chronic cough

July 27, 2023
By David Godkin
Deep learning algorithms are used to remotely monitor and track just about everything these days and now that includes ordinary and chronic cough. Hyfe Inc. has launched an AI-driven remote patient monitoring (RPM) program designed to monitor cough for a whole range of serious ailments at virtual hospitals, remote care and telehealth programs across the U.S.
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Lungs and bronchi

Insilico progresses AI-discovered drug to phase II trials in idiopathic pulmonary fibrosis

July 25, 2023
By Tamra Sami
Artificial intelligence (AI) drug discovery specialist Insilico Medicine Inc. is progressing INS018-055, its lead compound to phase II trials for idiopathic pulmonary fibrosis, a chronic lung disease that results in progressive and irreversible decline in lung function.
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Heart and lungs

Magassist moves forward with ECMO in China's heart failure market

July 21, 2023
By Doris Yu
Taking a step forward in an increasingly crowded market that has long been dominated by non-Chinese players, Magassist Co. Ltd. got positive clinical results from its extracorporeal membrane oxygenation (ECMO) system Breathmo to provide support for patients with serious heart failure or lung failure, with a study showing that the system can provide pulmonary and cardiac support effectively and safely.
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Respiratory

Chiesi Farmaceutici reports LPAR1 inhibitors for treatment of IPF

July 21, 2023
A Chiesi Farmaceutici SpA patent details cyclohexane acid derivatives acting as lysophosphatidic acid receptor 1 (LPAR1; EDG2) antagonists and thus reported to be useful for the treatment of idiopathic pulmonary fibrosis (IPF).
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Pill over molecule structures
Inflammatory

Recludix and Sanofi collaborate on oral STAT6 inhibitors for immunological and inflammatory diseases

July 21, 2023
Recludix Pharma Inc. has entered into a strategic collaboration with Sanofi SA to develop and commercialize first-in-class oral small-molecule STAT6 (signal transducer and activator of transcription 6) inhibitors for patients with immunological and inflammatory diseases. STAT6 is believed to play a key role in multiple dermatological and respiratory diseases.
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Lungs and bronchi

Insilico progresses AI-discovered drug to phase II trials in idiopathic pulmonary fibrosis

July 20, 2023
By Tamra Sami
Artificial intelligence (AI) drug discovery specialist Insilico Medicine Inc. is progressing INS018-055, its lead compound to phase II trials for idiopathic pulmonary fibrosis, a chronic lung disease that results in progressive and irreversible decline in lung function.
Read More
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