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BioWorld - Friday, July 4, 2025
Home » Topics » Disease categories and therapies » Respiratory

Respiratory
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Lee’s Pharm acquires lucinactant from Windtree in $78.9M deal

Aug. 30, 2022
By Doris Yu
Lee’s Pharmaceutical (HK) Ltd. and its affiliate, Zhaoke Pharmaceutical (Hefei) Co. Ltd., expanded their rights to lucinactant Surfaxin, lyophilized lucinactant Surfaxin LS and Aerosurf from Windtree Therapeutics Inc. in a $78.9 million global license deal to develop and commercialize the candidates for the treatment of preterm infants with respiratory distress syndrome and other potential indications.
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Natural killer cell

Japan’s Healios advances its iPSC-derived gene engineered killer cells toward the clinic

Aug. 30, 2022
By Tamra Sami
Japan’s Healios K.K. is in discussions with Japan’s Pharmaceutical and Medical Devices Agenc about the regulatory path forward for its Multistem somatic stem cell products, for which it conducted phase II/III trials in ischemic stroke and a phase II trial in acute respiratory distress syndrome.
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Lungs and bronchiole
Respiratory

Airway microbiome regulates chronic obstructive pulmonary disease

Aug. 30, 2022
By Mar de Miguel
A metabolite derived from the airway microbiome, indole-3-acetic acid (IAA), could become a potential therapeutic candidate for chronic obstructive pulmonary disease (COPD). Researchers at South China Normal University (SCNU) have shown how IAA prevents lung function decline by reducing inflammation, apoptosis and emphysema through IL-22 in the interaction between macrophages and alveolar epithelial cells.
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Natural killer cell

Japan’s Healios advances its iPSC-derived gene engineered killer cells toward the clinic

Aug. 26, 2022
By Tamra Sami
Japan’s Healios K.K. is in discussions with Japan’s Pharmaceutical and Medical Devices Agenc about the regulatory path forward for its Multistem somatic stem cell products, for which it conducted phase II/III trials in ischemic stroke and a phase II trial in acute respiratory distress syndrome.
Read More

Lee’s Pharm acquires lucinactant from Windtree in $78.9M deal

Aug. 26, 2022
By Doris Yu
Lee’s Pharmaceutical (HK) Ltd. and its affiliate, Zhaoke Pharmaceutical (Hefei) Co. Ltd., expanded their rights to lucinactant Surfaxin, lyophilized lucinactant Surfaxin LS and Aerosurf from Windtree Therapeutics Inc. in a $78.9 million global license deal to develop and commercialize the candidates for the treatment of preterm infants with respiratory distress syndrome and other potential indications.
Read More

Scripps Research Institute presents new DPP4 inhibitors

Aug. 18, 2022
Scripps Research Institute has synthesized dipeptidyl peptidase 4 (DPP4) inhibitors reported to be useful for the treatment of lung diseases.
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Bronchodilator RCD-405 shows relaxation activity in ex vivo human airways

Aug. 18, 2022
Preclinical data has been reported for RCD-405, which is being developed by Arcede Pharma, a spin-out from Respiratorius AB, for the treatment of severe asthma and chronic obstructive pulmonary disease (COPD).
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Breathing easier: Verona’s phase III in COPD hits primary and secondary endpoints

Aug. 9, 2022
By Lee Landenberger
Top-line data from Verona Pharma plc’s phase III ENHANCE-2 study show its inhaled ensifentrine hit the primary and secondary endpoints in treating chronic obstructive pulmonary disease (COPD). Next up: data from the companion phase III, ENHANCE-1, which is expected by the end of 2022.
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Businesswoman pressing dollar sign on touchscreen

Structure Therapeutics nets $33M in financing for GPCR candidates

Aug. 9, 2022
By Doris Yu
Structure Therapeutics Inc. raised $33 million in a financing round to speed up clinical trials of its lead assets targeting chronic diseases and to improve its technology platform. Previously known as Shouti Inc., the company also has rebranded itself as Structure to “reflect its foundation in structural biology and computational design.”
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New CFTR modulators discovered at AbbVie

Aug. 8, 2022
AbbVie has patented cystic fibrosis transmembrane conductance regulator (CFTR) (deltaF508 mutant) correctors reported to be useful for the treatment of cystic fibrosis.
Read More
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