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BioWorld - Tuesday, June 30, 2026
Home » Topics » Antibody-drug conjugate, BioWorld Science

Antibody-drug conjugate, BioWorld Science
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Immuno-oncology

Sichuan Kelun-Biotech divulges new HER2-targeting ADCs

Dec. 10, 2024
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has synthesized antibody-drug conjugates.
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Immuno-oncology

DLK1-directed immunotherapy shows activity in neuroblastoma models

Dec. 10, 2024
Researchers from the Children's Hospital of Philadelphia presented data from a study that aimed to identify novel biologically relevant cell surface immunotherapeutic targets for neuroblastoma.
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Immuno-oncology

Duality Biologics and GSK enter option agreement for ADC DB-1324

Dec. 4, 2024
Duality Biologics (Suzhou) Co. Ltd. has entered into an exclusive option agreement with GSK plc.
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Concept art for targeting cancer
Cancer

PYX-201 demonstrates antitumor activity across sarcoma subtypes

Nov. 26, 2024
Researchers from Pyxis Oncology Inc. presented preclinical data for PYX-201, an antibody drug conjugate (ADC) that targets extra domain B of fibronectin (EDB+FN).
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Light micrograph of fibrosarcoma, a type of soft tissue sarcoma
Cancer

Collagen receptor uPARAP-targeted ADCs are active in sarcoma models

Nov. 25, 2024
Researchers from KU Leuven presented novel urokinase plasminogen activator receptor-associated protein (uPARAP)-targeted antibody-drug conjugates (ADC), ADCE-017 and ADCE-202, being developed for the treatment of soft tissue sarcoma.
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3D rendering of drug linked to antibody
Immuno-oncology

Series B financing at Adcendo to fund ADC pipeline

Nov. 25, 2024

Adcendo ApS has closed an oversubscribed $135 million series B financing round to support its development of first-in-class antibody-drug conjugates (ADCs) for the treatment of cancers with a high unmet medical need.


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Lab glassware and antibodies art concept
Cancer

BB-201, a potent first-in-class anti-Her2/anti-Trop2 bispecific ADC candidate

Nov. 19, 2024
Researchers from Bright Biologics LLC presented the discovery and preclinical characterization of a novel bispecific anti-Her2/anti-Trop2 antibody-drug conjugate (ADC), BB-201.
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Immuno-oncology

Exelixis publishes characterization of anti-TF conjugate with strong antitumor efficacy

Nov. 18, 2024
Researchers from Exelixis Inc. described the preclinical characterization of XB-002, an antibody-drug conjugate consisting of a monoclonal antibody recognizing a tissue factor (TF) epitope that does not interfere with factor VII binding.
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Immuno-oncology

Bolt presents immune-stimulating antibody-drug conjugate

Nov. 14, 2024
Claudin (CLDN) 18.2 is a transmembrane tight junction protein overexpressed in multiple cancers, including gastric, esophageal and pancreatic cancers.
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Antibody-drug conjugate
Immuno-oncology

Preclinical characterization of ZW-220, a differentiated and Fc-silenced NaPi2b-targeted ADC

Nov. 11, 2024
Researchers from Zymeworks Inc. recently reported preclinical data for ZW-220, an antibody-drug conjugate (ADC) consisting of humanized IgG1 monoclonal antibody targeting sodium-dependent phosphate transport protein 2B (SLC34A2, NaPi2b) conjugated to a topoisomerase I inhibitor, being developed for the treatment of cancer.
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