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BioWorld - Sunday, December 21, 2025
Home » Topics » Antibody-drug conjugate, BioWorld Science

Antibody-drug conjugate, BioWorld Science
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Immuno-oncology

Myricx Bio licenses Wuxi antibody for ADC with NMTi-based payload

Nov. 22, 2023
Myricx Bio (Myricx Pharma Ltd.) and Wuxi Biologics Co. Ltd. have entered into a license agreement under which Myricx will have exclusive access to a proprietary antibody that was discovered based on Wuxi Bio's integrated technology platforms.
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Ovarian cancer illustration
Immuno-oncology

Medicovestor seed financing to advance platform and lead ADC

Nov. 21, 2023
Medicovestor Inc. has successfully completed an oversubscribed seed financing round with the aim of advancing its antibody-drug conjugate (ADC) platforms and drug candidates.
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Concept of business partnership
Immuno-oncology

Nona Biosciences and Genequantum collaborate to enhance technology platform capabilities

Nov. 13, 2023
Nona Biosciences, a wholly owned subsidiary of HBM Holdings Ltd., has entered into a strategic collaboration with Genequantum Healthcare (Suzhou) Co. Ltd. to advance the early discovery of next-generation bioconjugates.
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Immuno-oncology

New PTK7-directed antibody effective in preclinical cancer models

Nov. 10, 2023
Protein tyrosine kinase 7 (PTK7) is a pseudo tyrosine kinase overexpressed in many cancer types such as ovarian, triple-negative breast cancer (TNBC), non-small-cell lung cancer, small-cell lung cancer and bladder cancer, but limited expression in normal tissues.
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Antibody-drug conjugate illustration
Immuno-oncology

DM-005, a bispecific ADC with robust efficacy in preclinical models

Nov. 10, 2023
Researchers from Biocytogen Pharmaceuticals (Beijing) Co. Ltd. and Doma Biopharmaceutical (Suzhou) Co. Ltd. reported the discovery and preclinical data of DM-005, a novel fully human EGFR × MET bispecific antibody-drug conjugate (ADC) being developed for the treatment of cancer.
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Cancer

New ADCs reported in Debiopharm patent

Nov. 9, 2023
Debiopharm Research & Manufacturing SA has disclosed new antibody-drug conjugates consisting of monoclonal antibodies targeting CD37 covalently linked to a cytotoxic agent through a linker.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

ARX-305 demonstrates promising PK, efficacy and safety profile in preclinical models

Nov. 8, 2023
Researchers from Ambrx Inc. and Novocodex Biopharmaceuticals Co. Ltd. presented preclinical data for ARX-305, a next-generation anti-CD70 antibody-drug conjugate (ADC), being developed for the treatment of CD70-expressing cancers.
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Antibody-drug conjugate
Immuno-oncology

Angiex cleared to begin phase I study of TM4SF1-directed ADC

Nov. 3, 2023
Angiex Inc. has received FDA clearance of its IND application for AGX-101, a novel TM4SF1-directed antibody-drug conjugate (ADC) being developed for the treatment of solid cancers.
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Cancer

HLX-42 is EGFR-targeting ADC with activity in several cancer models

Oct. 31, 2023
Researchers from Shanghai Henlius Biotech Inc. presented the discovery and preclinical characterization of HLX-42, a next-generation EGFR-targeting antibody-drug conjugate (ADC) being developed for the treatment of cancer.
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Antibody-drug conjugate illustration
Immuno-oncology

HLX-43, a next-generation PD-L1-targeting antibody-drug conjugate

Oct. 27, 2023
There is a need for new agents targeting PD-1/PD-L1 because many patients either do not respond or develop resistance to treatment.
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