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Home » Topics » Drugs » Cell therapy

Cell therapy
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Human aging illustration

Juvenescence's $76M+ to advance CD38, ketone drugs to clinic

May 21, 2025
By Nuala Moran
No Comments
Anti-aging specialist Juvenescence Ltd. reached the first close of its series B-1 at $76 million and said it is on course to close the round at $150 million in the third quarter of 2025. “The reason for the first close and not waiting for the very end is just so we can start to move the pipeline forward,” said Richard Marshall, CEO. “We’ve got molecules in and waiting to go, so the sooner we can get going on those, the better,” he told BioWorld.
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Cancer cells being destroyed by immunotherapy
Cancer

Avidicure boosting immune activation with $50M seed round

May 19, 2025
By Nuala Moran
No Comments
Newco Avidicure NV arrived on the scene with a hefty $50 million in seed funding to advance novel antibody formats the company says will surpass the best qualities of first-generation antibodies, checkpoint inhibitors, T-cell engagers and antibody-drug conjugates.
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Illustration of kidneys with DNA double helix
Nephrology

ASGCT 2025: Overcoming kidney complexity in gene and cell therapy

May 16, 2025
By Mar de Miguel
No Comments
Gene and cell therapies (GCTs) can target the kidney to treat congenital, acute or chronic diseases affecting this organ. However, its complex structure poses a challenge for these technologies. To be precise and effective in the long term, new approaches should circumvent the specificities of renal tissue, with novel methods of delivery and gene transfer to offer new therapeutic options for patients who lack them.
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Cancer cells being destroyed by immunotherapy
Newco news

Avidicure boosting immune activation with $50M seed round

May 15, 2025
By Nuala Moran
No Comments
Newco Avidicure NV arrived on the scene with a hefty $50 million in seed funding to advance novel antibody formats the company says will surpass the best qualities of first-generation antibodies, checkpoint inhibitors, T-cell engagers and antibody-drug conjugates.
Read More
Illustration of liver with DNA double helixes
Endocrine/metabolic

ASGCT 2025: Gene and cell therapies transform metabolic diseases

May 15, 2025
By Mar de Miguel
No Comments
Metabolic disorders such as argininosuccinic and glutaric aciduria, methylmalonic acidemia, homocystinuria or primary hyperoxaluria require specific diets to prevent the accumulation of substances that the body can’t process. Current treatments mainly focus on managing symptoms and metabolite levels, and do not always prevent the progressive deterioration caused by mutations associated with the condition. However, emerging gene therapies hold promise for transforming these diseases by targeting their underlying causes, as presented in the oral abstract session, “Gene and cell therapy for metabolic diseases” of the ongoing 28th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT) meeting in New Orleans.
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3D illustration of mesenchymal stem cells

Cynata’s MSC cells show positive results across variety of delivery systems

May 13, 2025
By Tamra Sami
No Comments
The promise of mesenchymal stem cells (MSCs) to heal heart disease could be around the corner thanks to a new delivery method tested by regenerative medicine company Cynata Therapeutics Ltd.
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3D illustration of mesenchymal stem cells

Cynata’s MSC cells show positive results across variety of delivery systems

May 9, 2025
By Tamra Sami
No Comments
The promise of mesenchymal stem cells (MSCs) to heal heart disease could be around the corner thanks to a new delivery method tested by regenerative medicine company Cynata Therapeutics Ltd.
Read More
Red arrow pointing downward on a stock market ticker

Some unshod by Prasad nod as CBER change socks stocks

May 7, 2025
By Randy Osborne
No Comments
The appointment May 6 of Vinay Prasad as the head of the U.S. FDA’s Center for Biologics Evaluation and Research (CBER) “bodes poorly” for Sarepta Therapeutics Inc.’s development-stage pipeline, said Wainwright analyst Mitchell Kapoor – and Wall Street reflected as much, as the stock (NASDAQ:SRPT) ended that day down 26.6% vs. an XBI drop of 6.6% – this ahead of the after-hours earnings disclosure that pushed the Cambridge, Mass.-based firm down even farther by more than another 20%, with the XBI unchanged.
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More stringency expected under new CBER head

May 6, 2025
By Mari Serebrov
No Comments
U.S. FDA Commissioner Marty Makary is starting to fill the vacancies at the agency that’s seen its senior leadership ravaged by retirements and terminations. Makary’s first pick is Vinay Prasad as the new head of the FDA’s Center for Biologics Evaluation & Research (CBER), the center that oversees vaccines, blood products, allergenics and cellular, tissue and gene therapies.
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Human NK cell
Immuno-oncology

EMA grants IMPD approval for Emercell to study allogeneic NK cell therapy for DLBCL

April 25, 2025
Onward Therapeutics SA’s subsidiary Emercell SAS has received investigational medicinal product dossier (IMPD) approval from the EMA to initiate a phase I trial of OT-C001, an allogeneic natural killer (NK) cell therapy, in combination with an anti-CD20 monoclonal antibody, rituximab.
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