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BioWorld - Saturday, July 11, 2026
Home » Topics » Drugs » Immuno-oncology

Immuno-oncology
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Immuno-oncology

Myricx Bio licenses Wuxi antibody for ADC with NMTi-based payload

Nov. 22, 2023
Myricx Bio (Myricx Pharma Ltd.) and Wuxi Biologics Co. Ltd. have entered into a license agreement under which Myricx will have exclusive access to a proprietary antibody that was discovered based on Wuxi Bio's integrated technology platforms.
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Ovarian cancer illustration
Immuno-oncology

Medicovestor seed financing to advance platform and lead ADC

Nov. 21, 2023
Medicovestor Inc. has successfully completed an oversubscribed seed financing round with the aim of advancing its antibody-drug conjugate (ADC) platforms and drug candidates.
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Vial and syringe
Immuno-oncology

Voltron plans preclinical dose-finding study of VTX-0P4

Nov. 21, 2023
Voltron Therapeutics Inc., a portfolio company of Lucius Partners LLC, has finalized the protocol for a preclinical dose-ranging efficacy study of VTX-0P4, a protein-based cancer vaccine targeting prostate stem cell antigen (PSCA), a key target in the treatment of prostate cancer.
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Illustration of antibodies binding to human cell receptors
Immuno-oncology

AIM-104 has pan-allele SIRPα binding, lacks hematological toxicity

Nov. 20, 2023
Researchers from Apeximmune Therapeutics Inc. presented the discovery and preclinical evaluation of AIM-104, a novel potent pan-allele anti-SIRPα antibody for the treatment of cancer.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Immuno-oncology

Anti-LILRB1/LILRB2 bispecific antibody shows potent antagonist activity, in vivo efficacy

Nov. 17, 2023
Work at Laekna Therapeutics Shanghai Co. Ltd. has led to the discovery of a potent leukocyte immunoglobulin-like receptor subfamily B member 1/2 (LILRB1/LILRB2) antagonistic bispecific antibody, LAE-111, with improved antitumor activity.
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Lab research with pipette, microsope
Immuno-oncology

OR-641 promotes antitumoral responses through LILRB1/LILRB2 dual targeting

Nov. 17, 2023
Oncoresponse Inc. has presented preclinical data on OR-641 as a potential immunotherapeutic for cancer.
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Immuno-oncology

AZD-6422, a novel dnTGFββRII-armored, CLDN18.2-targeted CAR T therapeutic

Nov. 16, 2023
CLDN18 is a cell surface membrane protein involved in the formation of tight junctions, and the expression of its CLDN18.2 isoform has been observed in pancreatic, gastric and esophageal tumors.
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Macrophage illustration
Immuno-oncology

Sirpant-M granted US orphan drug designation for T-cell lymphoma

Nov. 16, 2023
Sirpant Immunotherapeutics Inc.’s lead product candidate, Sirpant-M (SI-101), has been awarded U.S. orphan drug designation for the treatment of T-cell lymphoma.
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Natural killer cell attacking cancer cell
Immuno-oncology

SNK-02 cell therapy clears tumors in HER2-driven tumor models

Nov. 15, 2023
Researchers from Nkgen Biotech Inc. have developed an anti-HER2 CAR NK cell therapy, named SNK-02, as a potential immunotherapeutic for HER2-overexpressing tumors. SNK-02 was tested in a xenografted murine model of cancer.
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Immuno-oncology

mNTX-250 vaccine eradicates HPV-16-expressing tumors in mice

Nov. 14, 2023
Certain types of human papillomavirus (HPV), named high-risk types, are known to be clearly associated with 60% of invasive cervical cancer cases. Prophylactic HPV vaccines are highly effective, but there is a need for new treatment options other than surgery.
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