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BioWorld - Thursday, December 18, 2025
Home » Topics » Drugs » Immuno-oncology

Immuno-oncology
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3D representation of tumor
Immuno-oncology

China’s NMPA clears CSPC Pharmaceutical’s SYS-6023 to enter clinic for solid tumors

March 21, 2024
CSPC Pharmaceutical Group Ltd. has obtained clearance by China’s National Medical Products Administration (NMPA) to conduct clinical trials in China with SYS-6023 for advanced solid tumors.
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Pill over molecule structures
Immuno-oncology

Astrazeneca reveals new oral, selective HPK1 inhibitor and prodrug to increase IO therapy response

March 21, 2024
Development and optimization of novel oral selective hematopoietic progenitor kinase 1 (HPK1) inhibitors for immuno-oncology (IO) treatment were reported by scientists from Astrazeneca plc in two presentations during the ACS meeting this week.
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Immuno-oncology

Abbvie discloses anti-SEZ6 antibody-drug conjugates

March 18, 2024
Abbvie Inc. has prepared and tested new antibody-drug conjugates comprising an antibody targeting seizure protein 6 homolog (SEZ6) covalently linked to DNA topoisomerase I inhibitors through a linker.
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DNA illustration
Immuno-oncology

Asgard Therapeutics financing to advance in vivo cell reprogramming

March 14, 2024
Asgard Therapeutics AB has announced a €30 million (US$32.7 million) series A financing to advance its first-in-class in vivo cell reprogramming platform for immuno-oncology.
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3D illustration of T cells fighting cancer
Newco news

Immunoscape to develop new, safe TCR therapies for solid tumors

March 12, 2024
By Marian (YoonJee) Chu
Seven years since the first approval of two chimeric antigen receptor T-cell therapies for hematological cancers, U.S. and Singapore-based Immunoscape Pte Ltd. is looking to develop novel T-cell receptor (TCR) therapeutics for solid tumors.
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Onko-innate CEO Jai Rautela and CSO NIcholas Huntington
Cancer

Onko-innate seeks targets thought to be undruggable

March 12, 2024
By Tamra Sami
A new spinout from Monash University in Melbourne, Australia, is tackling biology to better understand immune cell function and to find targets that were thought to be undruggable. Onko-innate co-founders Jai Rautela and Nicholas Huntington first worked together at Huntington’s lab at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne where they studied the role of natural killer (NK) cells in tumor immunology and discovered some interesting regulatory pathways for cytokine responses.
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Multiple myeloma cells in the bone marrow.
Immuno-oncology

Trispecific antibody SIM-0500 approved for trials in the US and China for multiple myeloma

March 12, 2024
Simcere Zaiming, a subsidiary of Simcere Pharmaceutical Group Ltd., has received approval from the FDA and China’s National Medical Products Administration (NMPA) to conduct clinical trials with SIM-0500 in patients with relapsed or refractory multiple myeloma.
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3D illustration of T cells fighting cancer
Newco news

Immunoscape to develop new, safe TCR therapies for solid tumors

March 7, 2024
By Marian (YoonJee) Chu
Seven years since the first approval of two chimeric antigen receptor T-cell therapies for hematological cancers, U.S. and Singapore-based Immunoscape Pte Ltd. is looking to develop novel T-cell receptor (TCR) therapeutics for solid tumors.
Read More
Antibodies attacking cancer cell
Immuno-oncology

Ono Pharmaceutical licenses NXI-101 from Nex-I

March 6, 2024
Ono Pharmaceutical Co. Ltd. has entered into a license agreement with Nex-I Inc. to develop and commercialize NXI-101.
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3D illustration of tumor
Immuno-oncology

Sonata Therapeutics partners with Champalimaud Foundation to advance SNT-3012

March 6, 2024
Sonata Therapeutics Inc. and the Champalimaud Foundation have announced a research collaboration for the development of Sonata’s SNT-3012 for the treatment of pancreatic and colorectal cancers.
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