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BioWorld - Friday, February 6, 2026
Home » Topics » Drugs » Immuno-oncology

Immuno-oncology
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Immuno-oncology

New CAR T-cells target CD79b for non-Hodgkin lymphoma

Jan. 15, 2025
A new study published in the Journal for Immunotherapy of Cancer has presented a promising advancement in chimeric antigen receptor (CAR) T-cell therapy for non-Hodgkin lymphoma (NHL).
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Immuno-oncology

Amanitin-based antibody-drug conjugate tested in pancreatic cancer

Jan. 15, 2025
A recent study has introduced a novel class of antibody-drug conjugates (ADCs) targeting trophoblast cell surface antigen 2 (TROP2), a protein overexpressed in pancreatic ductal adenocarcinoma (PDAC), one of the deadliest forms of cancer.
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3d illustration of ovarian cancer
Immuno-oncology

ERNA-101 extends survival in mice with ovarian cancer

Jan. 15, 2025
Eterna Therapeutics Inc. has released promising results from a preclinical study of its lead cell therapy product, ERNA-101, showing it reduced tumor burden and extended survival in mice with ovarian cancer.
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Immuno-oncology art concept
Immuno-oncology

Rise Therapeutics’ R-5780 gains IND clearance from FDA

Jan. 14, 2025
Rise Therapeutics LLC has gained IND clearance from the FDA to initiate a phase I trial of R-5780 in patients with cancer.
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Art concept for monoclonal antibodies
Immuno-oncology

Iteos Therapeutics advances anti-TREM2 monoclonal antibody toward IND filing

Jan. 13, 2025
Iteos Therapeutics Inc. is advancing EOS-215, an anti-TREM2 monoclonal antibody, toward an IND filing.
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AI-generated image for cancer cells observed under a microscope
Immuno-oncology

CSPC’s SYS-6041 cleared to enter clinic in China

Jan. 13, 2025
CSPC Pharmaceutical Group Ltd. has obtained clinical trial approval from China’s National Medical Products Administration (NMPA) for SYS-6041, an antibody-drug conjugate, for advanced solid tumors.
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Immuno-oncology

Series B financing at Normunity to advance T-cell engager into clinic

Jan. 13, 2025
Normunity Inc. has closed a $75 million series B financing to support its pipeline of novel anticancer therapies targeting untapped drug mechanisms. Proceeds from the financing will be used to advance Normunity’s lead program, NRM-823, a first-in-class T-cell engager.
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Gold wireframe handshake
Immuno-oncology

Zai Lab partners with Medilink on LRRC15 antibody-drug conjugate for solid tumors

Jan. 10, 2025
Zai Lab Ltd. has entered into a new strategic collaboration and worldwide license agreement with Medilink Therapeutics (Suzhou) Co. Ltd. to use Medilink’s TMALIN antibody-drug conjugate (ADC) platform.
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Lab glassware and antibodies art concept
Immuno-oncology

Sotio licenses fully human antibodies from Biocytogen to support SOT-109 development

Jan. 10, 2025
Sotio Biotech AS has announced the licensing of fully human antibodies from Biocytogen Pharmaceuticals (Beijing) Co. Ltd.
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Immuno-oncology

Mural Oncology nominates candidates from IL-18 and IL-12 programs

Jan. 10, 2025
Mural Oncology plc has nominated two new development candidates, one for its interleukin-18 (IL-18) program and one for its IL-12 program.
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