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Home » Topics » Drugs » Immuno-oncology

Immuno-oncology
Immuno-oncology RSS Feed RSS

Antibody-drug conjugate
Immuno-oncology

Formosa and Almac Discovery sign license agreement for EGFRxROR1 bispecific ADC

May 7, 2025
No Comments
Formosa Pharmaceuticals Inc. and Almac Discovery Ltd. have announced a global licensing agreement for development and commercialization of ALM-401, a first-in-class engineered bispecific antibody-drug conjugate (ADC) for the treatment of solid tumors characterized by the dual expression of EGFR and ROR1.
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Head and neck anatomy

Immutep’s efti shows strong survival data in head and neck cancer

May 6, 2025
By Tamra Sami
No Comments
Immutep Ltd. announced strong median overall survival of 17.6 months in cohort B of the TACTI-003 (Keynote-PNC-34) phase IIb trial that evaluated eftilagimod alfa in combination with Merck & Co.’s Keytruda (pembrolizumab) as first-line therapy in recurrent/metastatic head and neck squamous cell carcinoma in patients with PD-L1 expression below 1.
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Hand pointing to IPOs on line graph

Three Korea biotechs prep for May IPOs

May 6, 2025
By Marian (YoonJee) Chu
Among three Korean biotech companies slated to sell shares on the Korea Exchange this month, Immuneoncia Therapeutics Inc. is the latest to price a ₩33.9 billion (US$24 million) Kosdaq IPO for May 19. Regenerative cell therapy maker Organoid Sciences Ltd. and antibody-drug conjugate specialist Intocell Inc. are also gearing up for respective Kosdaq listings starting next week.
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Immuno-oncology

Xenothera details preclinical characterization of XON-9

May 6, 2025
No Comments
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-associated deaths worldwide.
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Head and neck anatomy

Immutep’s efti shows strong survival data in head and neck cancer

May 5, 2025
By Tamra Sami
No Comments
Immutep Ltd. announced strong median overall survival of 17.6 months in cohort B of the TACTI-003 (Keynote-PNC-34) phase IIb trial that evaluated eftilagimod alfa in combination with Merck & Co.’s Keytruda (pembrolizumab) as first-line therapy in recurrent/metastatic head and neck squamous cell carcinoma in patients with PD-L1 expression below 1.
Read More
Illustration of human papillomavirus particles
Immuno-oncology

Ad-E6/7-HR shows prophylactic and therapeutic preclinical efficacy in HPV-associated cancers

May 5, 2025
No Comments
Human papillomavirus (HPV), particularly the high-risk HPV16 subtype, is a major driver of certain cancers, including cervical, oropharyngeal, anal and penile cancers. The E6 and E7 proteins produced by HPV16 are known to play critical roles in the development of these malignancies, making them attractive targets for therapeutic interventions.
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Concept art for targeting cancer
Cancer

Dual-blocking anti-PD-1/VEGF bispecific conjugate demonstrates robust antitumor efficacy

May 5, 2025
No Comments
Programmed cell death protein 1 (PD-1) and vascular endothelial growth factor (VEGF) are often co-expressed in the tumor microenvironment. The combination of anti-PD-1 and anti-VEGF agents has been evaluated in patients with advanced non-small-cell lung cancer, with promising results from agents like ivonescimab, a PD-1/VEGF bispecific antibody.
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Immuno-oncology

KGX-105 shows promising preclinical profile as cancer immunotherapeutic

May 5, 2025
No Comments
Kangabio Co. Ltd. has developed and presented data for their EGFRxCD3 TCE prodrug KGX-105 for the treatment of EGFR-expressing solid tumors.
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Immuno-oncology

Tyligand develops new dual-action tumor immune agonists for cancer treatment

May 5, 2025
No Comments
Tyligand Bioscience Ltd. has reported data on TSN-222, their new cyclic dinucleotide designed as a dual-action tumor immune agonist (DATIA) compound.
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Hand pointing to IPOs on line graph

Three Korea biotechs prep for May IPOs

May 2, 2025
By Marian (YoonJee) Chu
Among three Korean biotech companies slated to sell shares on the Korea Exchange this month, Immuneoncia Therapeutics Inc. is the latest to price a ₩33.9 billion (US$24 million) Kosdaq IPO for May 19. Regenerative cell therapy maker Organoid Sciences Ltd. and antibody-drug conjugate specialist Intocell Inc. are also gearing up for respective Kosdaq listings starting next week.
Read More
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