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BioWorld - Friday, April 24, 2026
Home » Topics » Drugs » RNAi

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Liver illustration

Olix wins $630M deal from Eli Lilly for phase I MASH asset

Feb. 11, 2025
By Marian (YoonJee) Chu
Olix Pharmaceuticals Inc. walked the talk in realizing a new $630 million licensing deal with Eli Lilly and Co. for its cardiovascular and metabolic disease asset, OLX-702A (OLX-75016), rallying stock by 30% after it had largely recovered from a terminated deal with France’s Théa Open Innovation last year.
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Liver illustration

Olix wins $630M deal from Eli Lilly for phase I MASH asset

Feb. 10, 2025
By Marian (YoonJee) Chu
Olix Pharmaceuticals Inc. walked the talk in realizing a new $630 million licensing deal with Eli Lilly and Co. for its cardiovascular and metabolic disease asset, OLX-702A (OLX-75016), rallying stock by 30% after it had largely recovered from a terminated deal with France’s Théa Open Innovation last year.
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RNA
Cancer

Akribion harnessing G-dase E nuclease, with initial focus in cancer

Feb. 5, 2025
By Nuala Moran
Newco Akribion Therapeutics GmbH has raised €8 million (US$8.3 million) in a seed round to develop a new and potent class of RNA-targeted CRISPR nucleases, which, rather than cleaving specific nucleic acids, can destroy every type of nucleic acid in a cell.
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RNA
Newco news

Akribion harnessing G-dase E nuclease, with initial focus in cancer

Feb. 4, 2025
By Nuala Moran
Newco Akribion Therapeutics GmbH has raised €8 million (US$8.3 million) in a seed round to develop a new and potent class of RNA-targeted CRISPR nucleases, which, rather than cleaving specific nucleic acids, can destroy every type of nucleic acid in a cell.
Read More
Year in review 2024 - Asia deals and innovation

Major 2024 licensing deals confirm Asia’s ascent from copier to innovator

Dec. 31, 2024
By Tamra Sami and Marian (YoonJee) Chu
From local drug discovery to global innovation, economic uncertainty is taking a toll on China’s innovative biotech system, forcing local companies to weather unpredictable storms, investors said during the Chinabio Partnering Forum in Shanghai in September.
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Year in review 2024 - Asia deals and innovation

Major 2024 licensing deals confirm Asia’s ascent from copier to innovator

Dec. 30, 2024
By Tamra Sami and Marian (YoonJee) Chu
From local drug discovery to global innovation, economic uncertainty is taking a toll on China’s innovative biotech system, forcing local companies to weather unpredictable storms, investors said during the Chinabio Partnering Forum in Shanghai in September.
Read More
Illustration of siRNA structure
Cardiovascular

Huadong Medicine and Synerk to jointly develop siRNA drug

Dec. 30, 2024
Hangzhou Sino-US Huadong Medicine Co. Ltd. and Synerk Pharmatech (Suzhou) Co. Ltd. have entered into a strategic collaboration in which the two parties will jointly develop the small nucleic acid (siRNA) drug SNK-2726.
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Cardiovascular

SYH-2062 cleared for clinic in China for hypertension

Dec. 24, 2024
CSPC Pharmaceutical Group Ltd. has gained clinical trial approval from China’s National Medical Products Administration (NMPA) for SYH-2062 injection, a double-stranded small interfering RNA (siRNA) drug to treat hypertension.
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PYC advances PYC-003 to clinic for polycystic kidney disease

Dec. 3, 2024
By Tamra Sami
After raising AU$40 million (US$25.9 million) earlier this year to advance lead candidate VP-001 for treating retinitis pigmentosa type 11, PYC Therapeutics is now advancing PYC-003 to the clinic for polycystic kidney disease.
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Sarepta ‘secures future’ with massive Arrowhead collaboration

Nov. 26, 2024
By Jennifer Boggs
In the largest collaboration of 2024, Sarepta Therapeutics Inc. and Arrowhead Pharmaceuticals Inc. entered a sprawling global licensing deal that includes a swath of clinical and preclinical candidates targeting rare genetic diseases. Under the terms, Sarepta gains access to existing and potential future compounds derived from the RNAi platform developed by Arrowhead, with the latter eligible for payments potentially exceeding $11 billion.
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