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BioWorld - Wednesday, July 9, 2025
Home » Topics » Diagnostics » Liquid biopsy

Liquid biopsy
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Data supports accuracy and performance of Nucleix’s Bladder Epicheck in NMIBC surveillance

Sep. 24, 2020
By Meg Bryant
An independent analysis of studies of Nucleix Ltd.’s Bladder Epicheck demonstrate high diagnostic accuracy and performance in monitoring for disease recurrence in patients with non-muscle invasive bladder cancer (NMIBC).
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Illumina snaps up liquid biopsy-focused Grail for $8B

Sep. 21, 2020
By Meg Bryant
Following days of speculation, Illumina Inc. said today it will acquire liquid biopsy startup Grail Inc. for $8 billion in cash and stock, bringing back into the fold a company it spun out in 2016. The deal gives Illumina a major stake in the race the race to develop a less-invasive way to diagnose cancer. Since spinning out, Grail has raised nearly $2 billion from big-name investors with promises of a blood test for early cancer detection and is hoping to introduce its liquid biopsy as a laboratory-developed test (LTD) as early as next year.
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Genetron develops testing kit for China’s nationwide cancer screening program

Sep. 14, 2020
By Elise Mak
Precision oncology company Genetron Holdings Ltd. will help develop a liquid biopsy-based malignant tumor screening and early detection testing kit based on its mutation capsule technology.
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Freenome raises $270M in series C round for registration study of CRC liquid biopsy test

Aug. 26, 2020
By Cormac Sheridan
DUBLIN – Liquid biopsy developer Freenome Inc. has – literally – capitalized on its recent proof-of-concept AI-Emerge colorectal cancer (CRC) screening study by raising $270 million in a series C round that will enable the South San Francisco firm to complete its ongoing Preempt CRC registration study and to file for pre-market approval from the FDA.
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Biofidelity raises $12M for lung cancer mutation diagnostic

Aug. 24, 2020
By Nuala Moran
LONDON – Biofidelity Ltd. has raised US$12 million in a series A, enabling it to start commercialization of a novel, low-cost, chemistry-based diagnostic for detecting all actionable lung cancer mutations. The Cambridge, U.K.-based company claims the test can detect a single molecule of mutated DNA against the background of billions of healthy molecules in a patient sample, without the need for DNA sequencing.
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Cancer cell and DNA

FDA gives thumbs up to first liquid biopsy NGS CDx test

Aug. 10, 2020
By Liz Hollis
The U.S. FDA revealed good news for Guardant Health Inc. Specifically, the agency has given a thumbs up for Guardant360 CDx for tumor mutation profiling, also known as comprehensive genomic profiling (CGP), in patients with any solid malignant neoplasm. The Redwood City, Calif.-based company noted that this marked the first approval to combine next-generation sequencing (NGS) and liquid biopsy in one diagnostic test to guide treatment decisions. The assay previously was granted a breakthrough device designation.
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Thrive Earlier Detection scoops up $257M to propel early cancer detection test

July 29, 2020
By Meg Bryant
Liquid biopsy startup Thrive Earlier Detection Corp. has raised $257 million in a series B round led by Casdin Capital and Section 32. The funds will be used to finalize the design of its first product, Cancerseek, conduct a trial to support U.S. FDA approval and prepare for commercialization.
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Invitae hits bull’s-eye with blockbuster $1.4B Archerdx buy

June 22, 2020
By Liz Hollis
Invitae Corp. (NYSE:NVTA) saw its stock flying high June 22 on the news of its agreement to buy Archerdx Inc., with an eye toward enhancing cancer genetics and precision oncology. Investors appear to approve of the deal, with the company’s stock closing at $27.05, up $8.34 or 44.58%.
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Creatv blood test predicts response to lung cancer treatment

June 12, 2020
By Annette Boyle
Creatv Microtech Inc. has developed a simple blood test that can predict response to chemoradiation and consolidated immunotherapy in patients with non-small-cell lung cancer (NSCLC).
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C2i Genomics raises $12M series A to bring whole genome pattern recognition to liquid biopsy

June 12, 2020
By Stacy Lawrence
Whole genome sequencing is not part of treating patients in practice – or even involved in most clinical trials of drug candidates. But C2i Genomics Inc. is working to make that a reality. It applies pattern recognition to whole genome sequencing to create an individualized fingerprint for a given patient’s tumor. The New York-based startup has raised a $12 million series A round to back the development of its technology, which came out of Cornell and the New York Genome Center.
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