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BioWorld - Monday, June 8, 2026
Home » Topics » North America » U.S.

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U.S. Capitol building

BMS-Hengrui deal strikes panic in Washington

June 2, 2026
By Tamra Sami
No Comments
On the heels of the multibillion-dollar licensing deal between Bristol Myers Squibb Co. and Jiangsu Hengrui Pharmaceuticals Co. Ltd., Chairman John Moolenaar (R-MI), of the House Select Committee on the Chinese Communist Party, sent a letter to Treasury Secretary Scott Bessent urging him to add biotechnology as a prohibited technology under the Comprehensive Outbound Investment National Security (COINS) Act of 2025.
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Cybersecurity data lock

China launches long-awaited drug data protection rules

June 2, 2026
By Tamra Sami
No Comments
China’s National Medical Products Administration has issued final implementation measures for drug trial data protection that mark a significant step toward aligning China’s pharmaceutical intellectual property framework with global standards.
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Hanmi signage

Hanmi, Haisco win billion-dollar partnerships with Eli Lilly

June 2, 2026
By Marian (YoonJee) Chu
No Comments
Hanmi Pharmaceutical Co. Ltd. secured a $1.26 billion deal with Eli Lilly and Co. to out-license ex-Korea rights to sonefpeglutide (HM-15912), a Lapscovery-based glucagon-like peptide-2 analog in development for multiple indications, including an ongoing phase II study of short bowel syndrome. It was one of two billion-dollar Asian company deals signed by Lilly on June 1, with the second transaction involving Haisco Pharmaceutical Group Co. Ltd., of Beijing.
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Antibodies attacking cancer cell

ADCs, multispecific antibodies anchor $10B Pfizer-Innovent deal

June 2, 2026
By Marian (YoonJee) Chu
No Comments
Pfizer Inc. is paying Innovent Biologics Co. Ltd. $650 million up front and up to $9.85 billion in milestones, plus royalties, to collaborate across 12 early stage and de novo antibody-drug conjugates (ADCs) and multispecific antibodies for oncology.
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Sickle cell illustration

Fulcrum drops work on SCD drug pociredir; stock plummets

June 2, 2026
By Jennifer Boggs
No Comments
Shares of Fulcrum Therapeutics Inc. (NASDAQ:FULC) fell 54% after the company said it is discontinuing work on sickle cell disease (SCD) candidate pociredir, its only clinical-stage candidate, and reviewing strategic alternatives in the wake of the U.S. FDA’s safety concerns regarding the drug target.
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DNA double helix illustration with section being removed in red

FDA advises leveraging what’s already known in gene therapy R&D

June 2, 2026
By Mari Serebrov
No Comments
Rather than reinventing the wheel for every gene therapy that uses genome editing, the U.S. FDA is advising sponsors on leveraging existing knowledge, be it publicly available or platform-based, to more efficiently advance their products across multiple stages of development.
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Breast cancer cell

ASCO 2026: Celcuity’s positive phase III gets no love from investors

June 2, 2026
By Brian Orelli
No Comments
Minneapolis-based Celcuity Inc. was like the Rolling Stones at the 2026 American Society of Clinical Oncology annual meeting. The company reported positive phase III data for its pan-PI3K/mTORC1/2 inhibitor gedatolisib, but Celcuity (NASDAQ:CELC) couldn’t get any satisfaction from investors who sent shares down 25.7%, or $31.54, to $91.42 on June 2, 2026.
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3D illustration of kidney cross section

Travere expands rare kidney portfolio in $1B+ Everest deal

June 2, 2026
By Karen Carey
No Comments
Less than two months after winning FDA approval for a second indication for Filspari (sparsentan), Travere Therapeutics Inc. added to its rare kidney disease pipeline by exclusively licensing civorebrutinib from Everest Medicines Ltd. in a deal that could be worth more than $1.14 billion.
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Person holding stomach in pain

Cancer specter looming, Abtect effect in UC wallops Abivax

June 2, 2026
By Randy Osborne
No Comments
Although analysts liked the data – calling them “truly amazing” and “transformational” – Wall Street apparently had qualms about three cancer cases that turned up in phase III top-line data from the Abtect maintenance trial with obefazimod. Paris-based Abivax SA’s oral, first-in-class miRNA-124 enhancer performed well in adults with moderately to severely active ulcerative colitis (UC), but shares of (NASDAQ:ABVX) closed June 2 at $72.50, down 44%, or $57.19.
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Cancer cell, DNA illustration

ASCO 2026: Drugmakers go ‘WEE1’ for early data

June 2, 2026
By Brian Orelli
No Comments
At the 2026 American Society of Clinical Oncology annual meeting, multiple companies presented data for their drugs targeting WEE1, a checkpoint for the transition from G2 into mitosis. Aprea Therapeutics Inc. presented phase 1 data for its WEE1 inhibitor APR-1051 in patients with advanced solid tumors showing two patients with endometrial cancers achieved partial responses in the dose-escalation study. Likewise, Zentalis Pharmaceuticals Inc. had tantalizing early results from a phase Ib study showing azenosertib plus paclitaxel in patients with platinum-resistant ovarian cancer produced an overall response rate of 39% with a median progression-free survival of 7.3 months.
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