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BioWorld - Saturday, December 13, 2025
Home » Topics » Regulatory » NIH

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Microscope with laptop displaying histology image.
Immuno-oncology

Replay and Syena license NIH library of TCRs targeting cancer neoantigens

Dec. 20, 2023
Replay Holdings LLC has entered into an exclusive, worldwide license agreement with the National Institutes of Health (NIH) for intellectual property related to a library of T-cell receptors (TCRs) directed against multiple cancer neoantigens.
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Silhouette with keyhole
Substance Use & Poisoning

Delix awarded NIDA grant to support development of neuroplastogen for substance use disorders

Dec. 14, 2023
Delix Therapeutics Inc. has been awarded a $320,000 grant from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, to support the advancement of DLX-007.
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Monica Bertagnolli, NIH director

Bertagnolli confirmed as next US NIH director

Nov. 7, 2023
By Mari Serebrov
After nearly two years with an acting director, the U.S. NIH now has a confirmed leader. The Senate voted 62-36 Nov. 7 to confirm Monica Bertagnolli, a cancer surgeon and researcher, as the next director of the research agency.
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Gloved hand holding COVID-19 vaccine vial, syringe
Immune

NIAID selects Tonix’s COVID-19 vaccine candidate TNX-1800 for inclusion in Project Nextgen trials

Nov. 3, 2023
The National Institute of Allergy and Infectious Diseases (NIAID) is set to conduct a phase I trial with Tonix Pharmaceuticals Holding Corp.’s TNX-1800 (recombinant horsepox virus, live vaccine), a vaccine candidate to protect against COVID-19.
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Telehealth credited with boosting effectiveness of care for opioid-use disorder

Oct. 30, 2023
By Mark McCarty
Advocates of expanded use of telehealth in the U.S. may believe they have an unfairly high evidentiary bar to meet to bring payers on board, but that evidentiary requirement just received support from the National Institutes of Health (NIH).
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3D concept image of nanoparticle layers
Immuno-oncology

NCI grant supports development of Duo Oncology's DUO-307

Oct. 30, 2023
Duo Oncology Inc. has been awarded a Small Business Technology Transfer grant by the National Cancer Institute (NCI) to support the development of DUO-307, a combination nanomedicine that delivers cytotoxic polymer conjugated gemcitabine (PGEM) and an immune modulating chemokine receptor type 2 antagonist (CCR2a) to tumor tissue.
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Monica Bertagnolli, NIH director

Despite chair’s opposition, US NIH nominee gets HELPing hand

Oct. 25, 2023
By Mari Serebrov
After nearly two years with an unconfirmed acting director at its helm, the U.S. NIH is one step closer to finally having Senate-confirmed leadership to steer the agency in a time pressed with political agendas, pandemic concerns and the potential for what could be life-altering innovations. The Senate Health, Education, Labor and Pensions (HELP) Committee voted 15-6 Oct. 25 to favorably report Monica Bertagnolli’s nomination to the full Senate for a confirmation vote as the next NIH director.
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Sanders decries NIH’s ‘become-a-billionaire program’

Oct. 24, 2023
By Mari Serebrov
U.S. Sen. Bernie Sanders (I-Vt.) is calling for an investigation into the NIH’s proposed grant of an exclusive patent license for a late-stage cervical cancer drug to a small company linked to a former NIH researcher.
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Monica Bertagnolli, NIH director

Drug prices, deals shadow hearing of US NIH nominee

Oct. 18, 2023
By Mari Serebrov
A week before the U.S. Senate Health, Education, Labor and Pensions Committee is scheduled to vote on the confirmation of Monica Bertagnolli as the next NIH director, she faced a grilling by the committee fueled by drug pricing agendas and deals the Biden administration made with certain lawmakers to advance her nomination.
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Scientist in lab with microscope
Drug Design, Drug Delivery & Technologies

NIH funding supports Integral Molecular’s discovery of antibodies

Oct. 6, 2023
Integral Molecular Inc. has been awarded funding totaling $896,000 from the National Institutes of Health (NIH), which will support its discovery of antibodies against difficult and conserved protein targets.
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