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BioWorld - Saturday, April 4, 2026
Home » Topics » Regulatory » Patents

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Gastrointestinal

KIST and Neocannbio report new NO production inhibitors

March 4, 2026
The Korea Institute of Science and Technology (KIST) and Neocannbio Co. Ltd. have jointly identified compounds acting as nitric oxide (NO) production inhibitors with potential for the treatment of inflammatory bowel disease (IBD).
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Cancer

Chinese researchers report WRN inhibitors

March 3, 2026
Shanghai Aryl Pharmtech Co. Ltd. and Zhejiang Hisun Pharmaceutical Co. Ltd. have jointly identified Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors for use in the treatment of cancer.
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Cancer

PKMYT1 inhibitors divulged in Roche patent

March 3, 2026
F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have patented Myt1 kinase (PKMYT1) inhibitors for the treatment of cancer.
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Neurology/psychiatric

CHA University discovers AChE and BuChE inhibitors

March 3, 2026
CHA University has identified chalcone derivatives acting as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors potentially useful for the treatment of Alzheimer’s disease.
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Endocrine/metabolic

Rongchang Pharmaceutical identifies GLP-1R agonists

March 3, 2026
Rongchang Pharmaceutical (Zibo) Co. Ltd. has synthesized nitrogen-containing fused ring compounds acting as glucagon-like peptide 1 receptor (GLP-1R) agonists potentially useful for the treatment of obesity and diabetes.
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Inflammatory

Dice Alpha patents new IL-17A inhibitors

March 3, 2026
Dice Alpha Inc. has disclosed interleukin-17A (IL-17A) inhibitors designed for use in the treatment of psoriasis, rheumatoid arthritis, multiple sclerosis and more.
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Infection

Shionogi synthesizes new compounds for malaria

March 2, 2026
Work at Shionogi & Co. Ltd. has led to the discovery of fused-ring quinolone derivatives for the treatment of malaria.
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Cancer

Therapex patents new EGFR mutant inhibitors

March 2, 2026
Therapex Co. Ltd. has identified pyrimidine derivatives acting as EGFR (HER1; erbB1) mutant inhibitors described as potentially useful for the treatment of cancer.
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Neurology/psychiatric

New muscarinic M4 receptor antagonists reported in Sumitomo Pharma patent

March 2, 2026
Sumitomo Pharma Co. Ltd. has patented aminomethylcyclohexane derivatives acting as muscarinic M4 receptor antagonists. As such, they are described as potentially useful for the treatment of neurodegenerative diseases, cerebrovascular disorders, brain injury, movement and psychiatric disorders.
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Cancer

Frontier Medicines discovers GTPase KRAS/PI3Kα interaction inhibitors

March 2, 2026
Frontier Medicines Corp. has divulged GTPase KRAS/PI3Kα interaction inhibitors. They are intended for use in the treatment of cancer.
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