Shanghai Allist Pharmaceuticals Co. Ltd. has discovered pyridopyrimidines acting as GTPase KRAS mutant inhibitors reported to be useful for the treatment of cancer.
Medshine Discovery Inc. has divulged amide compounds acting as epidermal growth factor receptor (EGFR) mutant inhibitors reported to be useful for the treatment of cancer.
Alephoson Biopharmaceuticals Ltd. has disclosed peptide-drug conjugates comprising a cell-penetrating peptide covalently linked to melphalan that are reported to be useful for the treatment of retinoblastoma.
With an eye toward the future, the U.S. Patent and Trademark Office (USPTO) is seeking comment on artificial intelligence (AI) technologies and inventorship issues that may arise as AI takes on a bigger role in innovation.
Blueprint Medicines Corp. presents mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1) inhibitors reported to be useful for the treatment of cancer and viral infections.
Cytokinetics Inc. has patented ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) inhibitors reported to be useful for the treatment of cancer, obesity and cardiovascular, inflammatory, metabolic, muscle, neurological and renal disorders, among others.
Medshine Discovery Inc. has synthesized dual N-(2-aminophenyl)benzamide compounds acting as lysine-specific histone demethylase 1A (LSD1) and histone deacetylase 1 (HDAC1) inhibitors reported to be useful for the treatment of cancer.