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Home » Topics » Infection » Coronavirus

Coronavirus
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US HHS awards Shionogi $375M to develop COVID-19 PrEP therapy

Jan. 21, 2025
By Marian (YoonJee) Chu
Shionogi & Co. Ltd. won a $375 million project agreement from the Rapid Response Partnership Vehicle to develop its 3CL protease inhibitor, S-892216, as a long-acting injectable for COVID-19 pre-exposure prophylaxis. The project was awarded to New Jersey-based Shionogi Inc., a subsidiary of the Osaka, Japan-based pharmaceutical company. S-892216 is an investigational second-generation 3CL protease inhibitor in development as a long-acting injectable for prophylaxis treatment of SARS-CoV-2.
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US HHS awards Shionogi $375M to develop COVID-19 PrEP therapy

Jan. 17, 2025
By Marian (YoonJee) Chu
Shionogi & Co. Ltd. won a $375 million project agreement from the Rapid Response Partnership Vehicle to develop its 3CL protease inhibitor, S-892216, as a long-acting injectable for COVID-19 pre-exposure prophylaxis.
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Microscope and coronavirus illustration
Infection

Discovery of covalent inhibitors of SARS-CoV-2 PLpro

Jan. 17, 2025
Investigators at The Scripps Research Institute and Rensselaer Polytechnic Institute have designed novel covalent inhibitors of SARS-CoV-2 papain-like protease (PLpro) and assessed their drug properties in preclinical models.
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Twindemic diagnostic

Incheon team mints new diagnostic test tailored to ‘twindemics’

Jan. 16, 2025
By Marian (YoonJee) Chu
Researchers have developed a novel point of care (POC) diagnostic that can test for multiple respiratory viral infections simultaneously, including for the flu and COVID-19. The POC diagnostic tool leverages a novel, non-enzymatic signal amplification method, according to study lead Eunjung Kim, professor at Incheon National University (INU), whose team published the findings in Sensors and Actuators B: Chemical online November 2024.
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Other news to note for Jan. 15, 2025

Jan. 15, 2025
Additional early-stage research and drug discovery news in brief, from: Editas Medicine, Invivyd, TAE Life Sciences.
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Humanigen execs face US insider trading charges

Dec. 31, 2024
By Mari Serebrov
Rounding out a year of insider trading charges involving biopharma companies, the U.S. SEC reported Dec. 30 that it had filed a complaint against two top Humanigen Inc. executives, Cameron Durrant, CEO, and Dale Chappell, chief science officer, for trades based on insider knowledge of FDA actions.
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Global vaccine.png
Immune

Pan-vaccine candidate offers cross-protection from coronaviruses and influenza viruses in mice

Dec. 31, 2024
Novel vaccines that can effectively target both coronaviruses and influenza viruses would be desirable to counteract the significant health burden these respiratory pathogens pose.
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Biontech’s $1.26B vaccine royalty settlement clears path forward

Dec. 30, 2024
By Mari Serebrov
Biontech SE agreed to pay up to nearly $1.26 billion in two separate settlements to resolve royalty disputes with the U.S. NIH and the University of Pennsylvania related to the COVID-19 vaccine the company partnered with Pfizer Inc.
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COVID-19 research illustration
Biomarkers

miR-1-3p levels predict case severity in hospitalized COVID-19 patients

Dec. 13, 2024

Increasing evidence shows that circulating microRNAs (miRNAs) regulate biological processes involved in COVID-19 complications.


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COVID-19 research illustration
Biomarkers

miR-1-3p levels predict case severity in hospitalized COVID-19 patients

Dec. 10, 2024

Increasing evidence shows that circulating microRNAs (miRNAs) regulate biological processes involved in COVID-19 complications.


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