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BioWorld - Monday, July 20, 2026
Breaking News: Best of BioWorld Science: Q2Breaking News: New research identifies EBV antigen targets for MS therapiesBreaking News: Science fiction realized: BCI tech is here
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BioWorld Science, Cancer
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Cancer

Beijing Danatlas Pharmaceutical Technology patents new PARG inhibitors

Nov. 25, 2024
Beijing Danatlas Pharmaceutical Technology Co. Ltd. has disclosed poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Cancer

J Ints Bio’s JIN-001 enhances radiation and chemotherapy to treat glioblastoma

Nov. 25, 2024
J Ints Bio Co. Ltd. has announced research findings with JIN-001, in development in collaboration with MD Anderson Cancer Center, for the treatment of brain tumors.
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Cancer tumor in breast illustration
Cancer

CGT-6297 leads to tumor regression in breast cancer model

Nov. 25, 2024
Researchers from Cogent Biosciences Inc. have presented data on their PI3KA H1047R mutant inhibitor CGT-6297 PI3KA wild-type inhibitors can lead to toxicity issues such as hyperglycemia, gastrointestinal toxicity and skin reactions.
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Light micrograph of fibrosarcoma, a type of soft tissue sarcoma
Cancer

Collagen receptor uPARAP-targeted ADCs are active in sarcoma models

Nov. 25, 2024
Researchers from KU Leuven presented novel urokinase plasminogen activator receptor-associated protein (uPARAP)-targeted antibody-drug conjugates (ADC), ADCE-017 and ADCE-202, being developed for the treatment of soft tissue sarcoma.
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3D illustration of acute myeloid leukemia cells
Immuno-oncology

Hemogenyx gains IRB approval for trial of HEMO-CAR-T for AML

Nov. 25, 2024
Hemogenyx Pharmaceuticals plc has obtained approval by the institutional review board (IRB) of the company’s first clinical site to initiate a phase I trial of the company’s lead asset, HEMO-CAR-T, for the treatment of relapsed or refractory acute myeloid leukemia (AML) in adults.
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Cancer

Origenis, Oncobone partner for cancer bone metastasis assets

Nov. 25, 2024
Oncobone Ventures Ltd. and Origenis GmbH have signed a framework agreement to develop novel therapies targeting cancer bone metastasis. Origenis leverages its artificial intelligence (AI)-driven technology platform Molmind-Moresystem-Brainstorm to design innovative targeted small-molecule therapies.
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Immuno-oncology

CO-005 is potent new anti-CD47 fusion protein

Nov. 25, 2024
Researchers from Caedo Oncology AS presented the discovery and preclinical characterization of CO-005, a novel anti-CD47 fusion protein being developed for the treatment of lymphoma.
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3D rendering of drug linked to antibody
Immuno-oncology

Series B financing at Adcendo to fund ADC pipeline

Nov. 25, 2024

Adcendo ApS has closed an oversubscribed $135 million series B financing round to support its development of first-in-class antibody-drug conjugates (ADCs) for the treatment of cancers with a high unmet medical need.


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Breast cancer illustration
Cancer

Therabene molecules show promise in triple-negative breast cancer model

Nov. 22, 2024
Therabene Inc. has released promising preclinical results for two new novel molecules targeting aggressive cancers.
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Cancer

GSC-002639 shows antitumor efficacy against PIK3CA-mutant tumors

Nov. 22, 2024
Mutations in the PIK3CA gene are present in about 4% to 36% of cancers such as breast, ovarian, endometrial and colorectal cancer, among others.
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