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BioWorld - Saturday, December 20, 2025
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Home » Topics » BioWorld Science, Dermatologic

BioWorld Science, Dermatologic
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Dermatologic

Hangzhou Bio-Creativity Pharma-Tech patents new PI3Kγ inhibitors for atopic dermatitis

Jan. 24, 2025
Hangzhou Bio-Creativity Pharma-Tech Co. Ltd. has disclosed phosphatidylinositol 3-kinase γ (PI3Kγ) inhibitors reported to be useful for the treatment of atopic dermatitis.
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Endocrine/metabolic

Kexing Biopharm highlights progress across pipeline

Jan. 24, 2025
Kexing Biopharm Co. Ltd. has outlined progress in its cachexia and autoimmune pipelines, built upon its Kx-Body antibody technology platform and Kx-Fusion fusion protein technology platform.
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White strand of DNA
Biomarkers

Wnt/PCP signaling mediators identified as new markers in yellow nail syndrome

Jan. 20, 2025
Researchers from Tel Aviv Sourasky Medical Center presented data from a study that aimed to investigate the genetic mechanisms underlying yellow nail syndrome (YNS), a rare disorder characterized by three features, namely yellow dystrophic nails, lymphedema and chronic lung disease.
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Dermatologic

Targeting GluK2 combats mast cell activation and skin inflammation

Jan. 15, 2025
A recent study published in Science Translational Medicine has examined a new approach to address inflammatory skin diseases, such as dermatitis and rosacea, by focusing on a specific glutamate receptor in mast cells.
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Inflammatory

Gilead and Leo Pharma partner on oral STAT6 program

Jan. 13, 2025
Gilead Sciences Inc. and Leo Pharma A/S have established a strategic partnership to accelerate the development and commercialization of Leo’s small-molecule oral STAT6 programs for the treatment of inflammatory diseases.
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Dermatologic

Nimbus Therapeutics patents new 15-hydroxyprostaglandin dehydrogenase inhibitors

Jan. 8, 2025
Nimbus Therapeutics LLC has disclosed 15-hydroxyprostaglandin dehydrogenase inhibitors reported to be useful for the treatment of alopecia, muscle atrophy and more.
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Skin irritation on hands
Inflammatory

Kaken licenses STAT6 program to J&J

Dec. 27, 2024
Kaken Pharmaceutical Co. Ltd. and Johnson & Johnson (J&J) have entered into a license agreement for the global development, manufacturing and commercialization of a STAT6 program for autoimmune and allergic diseases, including atopic dermatitis (AD), developed by Kaken.
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Inflammatory

Deepcure discovers oral STAT6 inhibitors for type 2 inflammatory diseases

Dec. 20, 2024
Deepcure Inc. has discovered potent, selective oral small-molecule inhibitors of STAT6. These next-generation STAT6 inhibitors have demonstrated promising oral bioavailability, cell permeability and metabolic stability, and do not target STAT6 for degradation.
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Immune

TAVO-101, a potent anti-TSLP antibody with extended half-life

Dec. 19, 2024
Researchers from Tavotek Biotherapeutics Inc. described the discovery and preclinical characterization of TAVO-101.
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Dermatologic

New TYK2 inhibitors disclosed in Sunshine Lake Pharma patent

Dec. 16, 2024
Sunshine Lake Pharma Co Ltd. has divulged non-receptor tyrosine-protein kinase TYK2 inhibitors reported to be useful for the treatment of multiple sclerosis, psoriasis, rheumatoid arthritis, atopic dermatitis, scleroderma, lupus nephritis, systemic lupus erythematosus and ulcerative colitis, among others.
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