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BioWorld - Saturday, February 14, 2026
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Infection

Assembly Biosciences describes new azetidine compounds for HSV infections

June 18, 2025

Assembly Biosciences Inc. has identified azetidine compounds reported to be useful for the treatment of herpes simplex virus (HSV) infections. 


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Cancer

Shanghai Fosun Pharmaceutical patents new PARG inhibitors

June 18, 2025
Shanghai Fosun Pharmaceutical (Group) Co. Ltd. has synthesized poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Novartis divulges new HTT splicing modulators

June 18, 2025
Novartis AG has disclosed huntingtin (HTT; HD) (mutant) splicing modulators reported to be useful for the treatment of familial dysautonomia, Huntington’s disease and spinal muscular atrophy.
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Endocrine/metabolic

Ascletis Pharma discovers new GLP-1R agonists

June 17, 2025
Ascletis Pharma (China) Co. Ltd. has described glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), diabetes, obesity, metabolic syndrome and more.
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Cancer

New PARG inhibitors disclosed in 858 Therapeutics patent

June 17, 2025
858 Therapeutics Inc. has divulged poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Ariel Scientific Innovations describes new dolastatin 10 analogues and conjugates

June 17, 2025
Ariel Scientific Innovations Ltd. has identified dolastatin 10 analogues and its conjugates comprising another functional moiety and a linking moiety reported to be useful for the treatment of cancer.
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Neurology/psychiatric

University of Sydney divulges new TSPO ligands

June 17, 2025
University of Sydney has synthesized translocator protein (TSPO; PBR) (A147T mutant) ligands reported to be useful for the diagnosis and treatment of neurological disorders.
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Neurology/psychiatric

Biogen patents new HTT splicing modulators

June 17, 2025
Biogen Inc. has disclosed huntingtin (HTT; HD) (mutant) splicing modulators reported to be useful for the treatment of Huntington’s disease and spinal muscular atrophy (SMA).
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Neurology/psychiatric

Nanjing Mingde New Drug Research discovers new KCNQ2/3 activators

June 16, 2025
Nanjing Mingde New Drug Research Co. Ltd. has described potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators reported to be useful for the treatment of epilepsy.
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Cancer

New WRN inhibitors disclosed in Breakpoint Therapeutics patent

June 16, 2025
Breakpoint Therapeutics GmbH has divulged Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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