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Inhibiting DsbA inactivates resistance enzymes, sensitizing AMR bacteria to existing antibiotics

March 4, 2022

Biomind reports in vivo findings with DMT combination drug BMND-07

March 4, 2022

TRIM14 is a potential therapeutic target for treating inflammation-driven diseases

March 4, 2022

Engineered retinal cells stare daggers at peritoneal tumors

March 4, 2022

Phenanthroline derivative with antitumor activity in liver cancer models

March 4, 2022

Targeting alpha2-Na+/K+ ATPase improves tau pathology in vivo

March 4, 2022

Cornell University patents PROTACs targeting BET domain proteins

March 4, 2022

New mucolipin-1 agonists divulged by Casma Therapeutics

March 4, 2022

New prodrugs of PIN1 inhibitors discovered at the University of California

March 4, 2022

Abm Therapeutics identifies new AXL/PAK1/c-KIT/RET/MAP4K1 inhibitors

March 4, 2022

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SCAN is core circuit affected in Parkinson’s disease
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Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement, and tremor is one of its signatures. But it is a much more wide-ranging disorder,...
IL-22 and TL1A, a robust couple for diagnosing hidradenitis suppurativa
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Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with strong association with psoriasis and inflammatory bowel disease (IBD). While some...
TL1A is overexpressed in hidradenitis suppurativa
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Despite the availability of advanced therapeutic options, about 40%-50% of patients with hidradenitis suppurativa do not achieve significant improvement in...
Inhibiting the NLRP3 inflammasome for cognitive impairment, stroke
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Vascular cognitive impairment and dementia (VCID) and cerebral small vessel disease are among the leading causes of dementia, where inflammation is known to play...