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New 5-HT2 receptor agonists identified

Oct. 6, 2021

ViiV Healthcare discloses new anti-HIV compounds

Oct. 6, 2021

Researchers patent new glucose triptolide conjugates

Oct. 6, 2021

DYNE-101 shows efficacy in mouse model of myotonic dystrophy type 1

Oct. 6, 2021

Preclinical assessment of the novel GLP-1 receptor agonist GZR-18

Oct. 6, 2021

Onegene Biotechnology presents OGB-21502, a novel antifibrotic agent

Oct. 6, 2021

Depression's doldrums linked to diagnostic duality at ECNP

Oct. 5, 2021

New model provides insight into tau propagation in early Alzheimer's disease

Oct. 5, 2021

Taysha collaborates with UTSW on next-generation construct for the treatment of CLN7 disease

Oct. 5, 2021

KRP-A218, an oral PI4KB inhibitor, is a potent antiviral in vivo

Oct. 5, 2021

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Orexin OX2 receptor agonists have demonstrated the ability to enhance wakefulness in rodent models, as well as in nonhuman primates and patients with narcolepsy...
First-in-class ADC targeting DEM-TXX shows high preclinical efficacy
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Researchers at DEM Biopharma Inc. reported preclinical findings demonstrating the efficacy of DEM-301, a bifunctional antibody-drug conjugate (ADC) engineered to...
5-HT2R allosteric ligands attenuate cocaine use and seeking behavior
BioWorld Science
Serotonergic G-protein-coupled receptors (GPCRs), including the 5-HT2A receptor (5-HT2AR) and 5-HT2CR, are key regulators of cortical signaling pathways and...