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Tumor mutational burden correlates with high-MSI patients in CRC

March 10, 2020

BioPROTACs cut out middleman, and small molecule

March 10, 2020

Keeping stem cells quiescent enables greater ultimate potency

March 10, 2020

Ascentage cleared to begin new trials of APG-2575 in U.S. and China

March 9, 2020

Netherlands Cancer Institute plans phase I/Ib study of RMC-4630 with ERK inhibitor

March 9, 2020

Compugen releases new data from phase I study of COM-701 in advanced solid tumors

March 9, 2020

FDA approves Isturisa for Cushing's disease

March 9, 2020

ALRN-6924 upregulates P21 expression in AML/MDS patients

March 9, 2020

Algernon makes ifenprodil available for compassionate use for coronavirus

March 9, 2020

CytoDyn submits IND application to study leronlimab for COVID-19 respiratory complications

March 9, 2020

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Today's news in brief
BioWorld
BioWorld briefs for July 20, 2026.
ALN-5288 lowers tau levels in preclinical models
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Pathological tau accumulation is a key driver of neurodegeneration in Alzheimer’s disease (AD) and other tauopathies such as progressive supranuclear palsy....
Dual FAAH/MAGL inhibition targets Alzheimer’s disease hyperexcitability
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Reduced endocannabinoid signaling has been linked to neuronal hyperexcitability in Alzheimer’s disease (AD), suggesting that dual inhibition of fatty acid amide...
Capital remains selective in ‘barbell’ biotech market
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Signs of recovery are emerging in the biotechnology investment sector, although investors across Asia say that capital is flowing selectively to companies that...
PSB-229 reduces plaque burden in Alzheimer’s models
BioWorld Science
Pyroglutamate-modified amyloid-β (pE3-Aβ) is a highly pathogenic Aβ species that accumulates within amyloid plaques and contributes to aggregation,...