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DDS-04a demonstrates potent antimicrobial activity against Enterobacteriaceae variants

April 25, 2019

Melanocortin receptor signaling can cut both ways in obesity

April 25, 2019

Glycosylation controls proteasome activity via sequence editing

April 25, 2019

Signature matching for PARP inhibitors

April 25, 2019

TC BioPharm conducting phase I study of TCB-002 in AML

April 24, 2019

MET/SRC/CSF-1R inhibitor TPX-0022 shows antitumor activity, IND planned

April 24, 2019

FDA approves Skyrizi for moderate to severe plaque psoriasis

April 24, 2019

Tiziana's phase IIa trial of milciclib in advanced liver cancer passes interim safety review

April 24, 2019

Teva discontinues development of fremanezumab for cluster headaches

April 24, 2019

Innovent begins phase I trial of PD-1/PD-L1 bispecific antibody IBI-318

April 24, 2019

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SCAN is core circuit affected in Parkinson’s disease
BioWorld Science
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement, and tremor is one of its signatures. But it is a much more wide-ranging disorder,...
TL1A is overexpressed in hidradenitis suppurativa
BioWorld Science
Despite the availability of advanced therapeutic options, about 40%-50% of patients with hidradenitis suppurativa do not achieve significant improvement in...
Astellas’ ASP-2246 shows promise in stroke management
BioWorld Science
Astellas Pharma Inc. recently presented data regarding ASP-2246, a drug candidate comprised of an mRNA encoding the transcription factor NeuroD1 encapsulated in...
IL-22 and TL1A, a robust couple for diagnosing hidradenitis suppurativa
BioWorld Science
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with strong association with psoriasis and inflammatory bowel disease (IBD). While some...