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BioWorld - Tuesday, February 17, 2026
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Close up image of shoulder and back with severe urticaria or hives
Dermatologic

Enanta Pharmaceuticals expands immunology portfolio

Nov. 26, 2024
Enanta Pharmaceuticals Inc. has announced the expansion of its immunology portfolio with the nomination of a new development candidate and the introduction of a new discovery program.
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Cardiovascular

Secretome raises funding for STM-01 in heart failure, cardiomyopathy

Nov. 26, 2024
Secretome Therapeutics Inc. has closed a $20.4 million round of financing to support its development of therapies derived from neonatal cardiac progenitor cells.
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Illustration of tumor in the liver
Immuno-oncology

Novel T-cell engager AZD-9793 has improved therapeutic index

Nov. 26, 2024
Researchers from Astrazeneca plc presented the discovery and preclinical characterization of AZD-9793, a novel CD8-guided T-cell engager (TCE) being developed for the treatment of hepatocellular carcinoma (HCC).
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Concept art for targeting cancer
Cancer

PYX-201 demonstrates antitumor activity across sarcoma subtypes

Nov. 26, 2024
Researchers from Pyxis Oncology Inc. presented preclinical data for PYX-201, an antibody drug conjugate (ADC) that targets extra domain B of fibronectin (EDB+FN).
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Cancer

Anocca submits CTA for TCR T umbrella trial in advanced pancreatic cancer

Nov. 26, 2024

Anocca AB has submitted its first clinical trial application (CTA) to the EMA for a phase I/II multi-asset umbrella trial, VIDAR-1. The application covers ANOC-001 as the initial product in the VIDAR-1 program targeting mutated KRAS in advanced pancreatic cancer. 


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Mast cell releasing histamine during allergic response
Immune

Longbio’s LP-003 receives NMPA clearance to enter clinic for food allergy

Nov. 26, 2024
Longbio Pharma (Suzhou) Co. Ltd. has obtained IND approval from China’s National Medical Products Administration (NMPA) for LP-003, the company’s next-generation anti-IgE antibody, to enter a clinical trial for the treatment of food allergy.
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Illustration of muscle tissue anatomy
Musculoskeletal

Dystrophies affect not just muscles; can RNA editing help?

Nov. 26, 2024
By Mar de Miguel
At the Breakthroughs in Muscular Dystrophy special meeting held in Chicago Nov. 19-20, 2024, and organized by the American Society of Gene & Cell Therapy (ASGCT), multiple interventions at the RNA level were among the approaches that were presented to fight muscular dystrophies.
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Bladder cancer illustration
Cancer

Radiopharma Telix acquires FAP-targeting agents for bladder cancer

Nov. 25, 2024
By Tamra Sami
Radiopharmaceutical company Telix Pharmaceuticals Ltd. has inked a deal worth up to AU$264 million (US$171 million) to license and develop next-generation radiopharma imaging and therapy technology targeting fibroblast activation proteins found in a wide range of cancers.
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Cancer

Hebei Wutu Pharmaceutical divulges new TRPV4 antagonists

Nov. 25, 2024
Hebei Wutu Pharmaceutical Co. Ltd. has synthesized transient receptor potential cation channel subfamily V member 4 (TRPV4) antagonists reported to be useful for the treatment of liver cancer, cirrhosis, hepatic fibrosis, chronic hepatitis B and liver failure.
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Inflammatory

Nanjing Mingde New Drug Research describes new NLRP3 inflammasome inhibitors

Nov. 25, 2024
Nanjing Mingde New Drug Research Co. Ltd. has identified NLRP3 inflammasome inhibitors reported to be useful for the treatment of inflammation.
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