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BioWorld - Sunday, June 21, 2026
Home » Topics » Biomarkers, BioWorld Science

Biomarkers, BioWorld Science
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Illustration of tick penetrating skin into blood stream
Biomarkers

MCP-3 predicts prognosis of severe fever with thrombocytopenia syndrome

April 30, 2024
Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne disease that results from an infection with the SFTS virus, with a case fatality rate of 6.1% to 21.8%. Identifying critically ill patients at the early stages is crucial for clinical management.
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Biomarkers

CD169 is a diagnostic marker of West Nile virus infection

April 29, 2024
About 25% of subjects with West Nile virus (WNV) infection develop fever and about 1% have neuroinvasive disease. Recent research has proposed measuring CD169 in peripheral blood (monocyte/lymphocyte ratio) as a marker of viral infections. The usefulness of monocyte CD169 (mCD169) in peripheral blood was tested in subjects with active WNV infection.
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Lymph nodes
Biomarkers

ZNF334 down-regulation linked to lymph node metastasis in lung squamous cell carcinoma

April 24, 2024
Lung cancer is still among the deadliest cancers worldwide, with squamous cell carcinoma (SCC) of the lung accounting for about 30% of the cases. When the cancer metastasizes to the lymph nodes, the patient has a worse overall survival.
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Medically accurate illustration of a baby in the womb of a pregnant mother
Cardiovascular

Peripartum cardiomyopathy is associated with placental senescence

April 24, 2024
By Mar de Miguel
Scientists at Massachusetts General Hospital have linked the risk of heart failure during pregnancy and senescence proteins produced by placental aging, which could clarify how peripartum cardiomyopathy (PPCM) is triggered and opens the door to the development of cardiac function therapies in late pregnancy.
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DNA sequencing
Biomarkers

Mutation in DAAM2 causes steroid-resistant nephrotic syndrome

April 19, 2024
Steroid-resistant nephrotic syndrome (SRNS) is a disease characterized by hypoalbuminemia, proteinuria, edema and hyperlipidemia, and a cause of chronic kidney disease in the pediatric population.
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Illustration of kidney with DNA structures
Biomarkers

Mutation in the UMOD gene tied to autosomal dominant tubulointerstitial kidney disease

April 18, 2024
Unknown etiology is commonly encountered in the kidney pre-transplant routine program. A screening program was performed to detect patients and study recipients that meet the following features: hypertension with no clear etiology and biopsies that do not match with clinical features of classical glomerulopathies.
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Biomarkers

KANK2 G690C genetic variant tied to nephrotic syndrome and FSGS

April 17, 2024
Nephrotic syndrome is a kidney disorder characterized by abnormal functioning of the glomerular filtration barrier, and is frequently caused by focal segmental glomerulosclerosis (FSGS). At the World Congress of Nephrology meeting this week, researchers presented a case report of a 32-year-old female patient with nephrotic syndrome caused by FSGS diagnosed when she was 27.
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HIV-1 virus particle
HIV/AIDS

Autophagy gene polymorphism protects against HIV-1 disease pathogenesis

April 16, 2024
The autophagy process, a critical regulator of T-cell function, has been shown to control acute HIV-1 infection and play a crucial role also in HIV-1 disease pathogenesis.
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Breast cancer illustration
Biomarkers

PDZK1 sensitizes TNBC cells to EGFR inhibitor erlotinib

April 15, 2024
Epidermal growth factor receptor (EGFR) is highly expressed in several cancer types, including triple-negative breast cancer (TNBC).
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Dividing breast cancer cell.
Biomarkers

ZCCHC3 is a prognostic marker in TNBC

April 11, 2024
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with poor prognosis and limited therapeutic options, and it accounts for 15%-20% of female invasive breast cancers.
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