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BioWorld - Monday, June 16, 2025
Home » Topics » Science » Biomarkers

Biomarkers
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Biomarkers

Validation of NKX6.2 as novel marker for duodenal neuroendocrine tumors

March 15, 2023
Researchers from the University of Pittsburgh Medical Center and affiliated organizations aimed to validate a novel marker of duodenal neuroendocrine tumors (DNETs), NKK6.2.
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Biomarkers

Study reveals hypermethylated miRNAs in epithelial ovarian cancer

March 14, 2023
Epithelial ovarian cancer (EOC) is difficult to treat due to its advance stage. The study of...
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Stomach and intestine
Biomarkers

Post-acute sequelae of COVID-19 associated with increased gut permeability and oxidized lipids

March 10, 2023
Researchers from Case Western Reserve University presented data from a study that aimed to investigate gut integrity, oxidized lipids and inflammatory markers associated with the pathogenesis of post-acute sequelae of COVID-19 (PASC).
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Biomarkers

Study unveils markers of higher mortality in perinatally infected HIV+ children

March 10, 2023
The mechanisms behind the mortality associated with early antiretroviral therapy (ART) treatment in children infected perinatally with HIV are poorly understood. Researchers sought to find potential biomarkers associated with the increased mortality. They created three groups of subjects: deceased (dead HIV+, n=20), nondeceased HIV+ (HIV+, n=59) and healthy controls (n=13).
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Biomarkers

CD33 plasma levels as marker of virus control in people with HIV

March 10, 2023
Researchers from IrsiCaixa Institute for AIDS Research presented data from a study that aimed to identify biomarkers associated with virus control during monitored antiretroviral pause (MAP) in patients with HIV.
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Biomarkers

Study reveals novel methylation markers associated with anal cancer risk in HIV

March 7, 2023
To date, there is a lack of consensus in anal cancer screening. DNA methylation markers zing finger protein 582 (ZNF582) and achaete-scute homolog 1 (ASCL1) have been associated with anal intraepithelial neoplasia (AIN3) and anal carcinoma risk in people with HIV infection.
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Biomarkers

sCD40L and D-dimer modulate risk of aortic aneurism in people with HIV

March 7, 2023
People with HIV have a 4-fold greater risk of developing an aortic aneurism (AA) than people without infection, but there is a lack of...
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Biomarkers

I-FABP and sCD14, markers of GI permeability that are elevated in patients with idiopathic anaphylaxis

March 6, 2023
Since episodes of idiopathic anaphylaxis (IA) are often accompanied by gastrointestinal (GI) manifestations, researchers from the National Institutes of Health aimed to investigate whether surrogate markers of GI permeability are aberrant in patients with IA.
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Liver anatomy illustration
Biomarkers

Identification of new risk-associated loci in primary sclerosing cholangitis

March 3, 2023
Primary sclerosing cholangitis (PSC) is a rare chronic and progressive autoimmune bile duct disease that is strongly associated with several immune-mediated disorders, the shared etiology and underlying characteristics of which is not completely understood. Researchers from Baylor College of Medicine investigated the shared genetic architecture of PSC with a variety of clinical and epidemiological traits and aimed to identify new lead PSC risk-associated loci.
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Biomarkers

RELMβ as novel biomarker and pathogenic player in children with food allergy

March 2, 2023
Resistin-like molecule beta (RELMβ) is a gut-derived cytokine involved in both allergic responses and protection from pathogens, and it has been previously found to be dysregulated in mouse models of food allergy (FA). Researchers from Boston Children’s Hospital aimed assess the potential of RELMβ as a novel biomarker in children with FA.
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