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BioWorld - Monday, October 2, 2023
Home » Topics » Drug design, drug delivery and technologies, BioWorld Science

Drug design, drug delivery and technologies, BioWorld Science
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Nobel Prize graphic with illustrations of Katalin Karikó and Drew Weissman
Infection

Perseverance on mRNA therapy research wins the 2023 Nobel Prize in Medicine after saving millions of lives

Oct. 2, 2023
By Mar de Miguel
No Comments
Researchers who follow their instincts and achieve slow results while trying to break barriers have little support. They replace it with persistence. This is the story of Katalin Karikó and Drew Weissman. What was once a dream in their minds was later a success. Their work together for decades was essential to achieving mRNA vaccines, and their perseverance was rewarded today with the 2023 Nobel Prize in Medicine.
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Drug research
Drug Design, Drug Delivery & Technologies

Quris and Merck KGaA extend collaboration using BioAI drug safety platform

Sep. 29, 2023
No Comments
Quris Technologies Ltd. (Quris-AI) and Merck KGaA have extended their collaboration after a successful initial preclinical study of Quris-AI’s BioAI drug safety platform.
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RNA illustration
Drug Design, Drug Delivery & Technologies

Deep Genomics announces AI foundation model for RNA

Sep. 28, 2023
No Comments
Deep Genomics Inc. has introduced its artificial intelligence (AI) foundation model for RNA, BigRNA, which enables discovery of disease mechanisms and candidate therapeutics.
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Mosaic illustration of a mouse
Neurology/Psychiatric

Genetic editing of individual cells points to late targets for developmental disorders

Sep. 28, 2023
By Mar de Miguel
No Comments
A new gene editing method uses the CRISPR technique to modify the cells of an organ in vivo, creating a mosaic used to identify the effects of each altered gene. Scientists from the Swiss Federal Institute of Technology (ETH) in Zürich developed this technology called AAV-Perturb-seq, based on adeno-associated virus (AAV) to target, edit and analyze single-cell genetic perturbations.
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Molecule illustration
Drug Design, Drug Delivery & Technologies

Orionis Biosciences collaborates with Genentech to discover molecular glues

Sep. 21, 2023
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Orionis Biosciences BV has established a multiyear collaboration with Genentech Inc., a member of the Roche Group, to discover novel small-molecule molecular glues for targets in major disease areas, including oncology and neurodegeneration.
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3D rendering conceptualizing theranostics
Drug Design, Drug Delivery & Technologies

Peptidream collaborates with Genentech on discovery and development of peptide-radioisotope drug conjugates

Sep. 20, 2023
No Comments
Peptidream Inc. has entered into a new multitarget collaboration and license agreement with Genentech, a member of the Roche Group, focused on the discovery and development of novel macrocyclic peptide-radioisotope drug conjugates.
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Illustration of pill being analyzed
Drug Design, Drug Delivery & Technologies

Benevolentai and Merck KGaA enter drug discovery and development collaboration

Sep. 20, 2023
No Comments
Benevolentai Ltd. has signed a strategic collaboration with Merck KGaA to identify novel drug candidates, initially for three targets in oncology, neurology and immunology.
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Art concept for gene therapy research
Genetic/Congenital

Machine learning tool Alphamissense analyzes human mutations to predict diseases

Sep. 19, 2023
By Mar de Miguel
No Comments
Proteome analysis with artificial intelligence has made it possible to create a catalog of all possible missense mutations in the human genome to predict diseases. The new Alphamissense tool from the technology company Google Deepmind, available online, will allow scientists to refine diagnoses and design more tailored treatment strategies for patients suffering from pathologies associated with these variants.
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Microscope with beakers and flasks
Drug Design, Drug Delivery & Technologies

Dewpoint and Chemify partner on molecules targeting condensates in oncology and neurodegeneration

Sep. 13, 2023
No Comments
Dewpoint Therapeutics Inc. and Chemify Ltd. have partnered to develop a suite of digitally discovered and automatically synthesized novel molecules on Chemify’s programmable chemistry platform against condensate targets of interest in Dewpoint’s oncology and neurodegeneration pipeline.
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Scientist looking in microscope, chemical structure concept image
Drug Design, Drug Delivery & Technologies

Biomarin outlines progress of preclinical pipeline

Sep. 13, 2023
No Comments
Biomarin Pharmaceutical Inc. has reported progress across its research and development portfolio, including early-stage product candidates.
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