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AbbVie constructs anti-TNF-alpha antibody-steroid antibody-drug conjugate for rheumatoid arthritis

Nov. 22, 2019

New ASK1/TAK1 dual kinase inhibitor for treating NASH presented

Nov. 20, 2019

RQ-00490721 prevents cardiac dysfunction in mouse model of heart failure

Nov. 20, 2019

DRA inhibitors synthesized for cystic fibrosis-related nephrolithiasis

Nov. 18, 2019

First-in-class fusion inhibitor against diverse and multidrug-resistant HCV strains presented

Nov. 14, 2019

Small-molecule STING agonist promotes durable antitumor immunity causing complete tumor regression

Nov. 13, 2019

MRX-1669, a novel small-molecule Myc inhibitor with promising in vitro activity

Nov. 12, 2019

Boehringer Ingelheim reports data on new SOS1-KRAS interaction inhibitors for cancer

Nov. 7, 2019

ABSK-041, a highly potent and orally available small-molecule PD-L1 antagonist

Nov. 7, 2019

EOLO-42016 shows promise in model of inherited ALS

Nov. 6, 2019

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Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with strong association with psoriasis and inflammatory bowel disease (IBD). While some...
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Vascular cognitive impairment and dementia (VCID) and cerebral small vessel disease are among the leading causes of dementia, where inflammation is known to play...
VST Bio’s VB-001 is neuroprotector after stroke
BioWorld Science
At the recent International Stroke Conference, researchers from VST Bio Corp. and Yale University presented preclinical data regarding VB-001, a monoclonal...
New mechanism of action identified for QC-6352
BioWorld Science
QC-6352 is a small molecule developed to inhibit the histone demethylase 4 (KDM4) that has shown potent antitumoral activity and which has a derivative named...