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BioWorld - Sunday, May 31, 2026
Home » Topics » Disease categories and therapies » Aging

Aging
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Cross section of brain
Neurology/psychiatric

Women more prone to AD even though their brains age better

Oct. 21, 2025
By Xavier Bofill Bruna
No Comments
Do men’s and women’s brains age equally? Women are more often diagnosed with Alzheimer’s disease (AD) than men. Age is the primary known risk factor for AD prevalence, and both aging and AD are associated with brain atrophy, but it is still not clear whether men and women differ regarding brain decline in aging. There is mixed evidence regarding this topic, since most of the larger studies have shown an abrupt decay of total gray matter and hippocampal volume in men, but other studies have found steeper total gray matter decline in women.
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Pomdoctor

Pomdoctor closes $20M IPO to grow mobile health platform in China

Oct. 10, 2025
By Marian (YoonJee) Chu
Pomdoctor Ltd. raised $20 million through a Nasdaq IPO on Oct. 8, with the funds geared to expand its mobile health platform for chronic diseases in China.
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Hand holding thin piece of film

Taho submits US NDA for first apixaban oral dissolving film

Oct. 7, 2025
By Marian (YoonJee) Chu
No Comments
Taho Pharmaceuticals Ltd. announced an NDA submission to the U.S. FDA for TAH-3311, developed as the world’s first oral dissolving film formulation of apixaban, marking a regulatory milestone for the Taipei-based biotech.
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Cancer diagnostic illustration
Cancer

New AI model can assign certainty, or uncertainty, to predictions

Oct. 7, 2025
By Marian (YoonJee) Chu
No Comments
A team of U.S. and South Korean researchers have developed an AI model called MSI-SEER that can not only predict microsatellite instability-high (MSI-H) tumors based on tissue slides, but also flag “what it does not know.” “Have you ever asked ChatGPT anything, and the response was, ‘I don’t know?’” Cheong Jae-ho asked during an interview with BioWorld. “Probably not, and that is the problem with AI now.”
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Hand holding thin piece of film

Taho submits US NDA for first apixaban oral dissolving film

Oct. 2, 2025
By Marian (YoonJee) Chu
No Comments
Taho Pharmaceuticals Ltd. announced an NDA submission to the U.S. FDA for TAH-3311, developed as the world’s first oral dissolving film formulation of apixaban, marking a regulatory milestone for the Taipei-based biotech.
Read More
Human SCNT oocyte with visible spindle before fertilization.
Gynecology/obstetrics

Fertilizable egg-like cells generated with DNA from skin cells

Oct. 1, 2025
By Mar de Miguel
No Comments
Generating gametes from nonreproductive tissues could help overcome infertility. Previous studies have successfully transformed stem cells into viable oocytes through cellular reprogramming. Scientists at Oregon Health & Science University (OHSU) developed a method to derive them from skin cells via somatic cell nuclear transfer (SCNT), unlocking a mechanism that blends mitosis and meiosis. Now, the researchers have taken another step forward by generating fertilizable eggs from human skin cells.
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Multiple sclerosis-damaged myelin
Neurology/psychiatric

Cellular senescence may trigger MS progression

Sep. 29, 2025
By Xavier Bofill Bruna
No Comments
Is there a link between cellular senescence and multiple sclerosis (MS) progression? Several presentations at this year’s European Committee for Treatment and Research in Multiple Sclerosis 2025 (ECTRIMS 2025) conference, in Barcelona, which ended Sept. 26, addressed this question
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Multiple sclerosis-damaged myelin
Neurology/psychiatric

Cellular senescence may trigger MS progression

Sep. 26, 2025
By Xavier Bofill Bruna
No Comments
Is there a link between cellular senescence and multiple sclerosis (MS) progression? Several presentations at this year’s European Committee for Treatment and Research in Multiple Sclerosis 2025 (ECTRIMS 2025) conference, which ends today in Barcelona, addressed this question.
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Illustration of damaged nerve cell and amyloid plaques
Biomarkers

pTau217 could change how Alzheimer’s is diagnosed

Sep. 23, 2025
By Mar de Miguel
No Comments
Experts agree that the earlier Alzheimer's disease is detected, the sooner action can be taken. And so, the key to preventing deterioration is identifying the most effective early biomarkers, those that can spot the disorder and help halt its progression. Recent advances in the field have pushed a new era of early detection through blood-based biomarkers and personalized medicine strategies based on each patient’s genetic, immunological and clinical profile.
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Illustration of damaged nerve cell and amyloid plaques
Biomarkers

pTau217 could change how Alzheimer’s is diagnosed

Sep. 22, 2025
By Mar de Miguel
No Comments
Experts agree that the earlier Alzheimer's disease is detected, the sooner action can be taken. And so, the key to preventing deterioration is identifying the most effective early biomarkers, those that can spot the disorder and help halt its progression. Recent advances in the field have pushed a new era of early detection through blood-based biomarkers and personalized medicine strategies based on each patient’s genetic, immunological and clinical profile.
Read More
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