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Home » Topics » Disease categories and therapies » Aging

Aging
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AI-generated depiction of lungs affected by cystic fibrosis
Respiratory

‘Remarkable’ progress in cystic fibrosis means more work needed

Feb. 28, 2025
By Nuala Moran
The map of cystic fibrosis (CF) research is being redrawn in the U.K. as improvements in treatment, and in particular the introduction of CF modulator drugs, mean people with the rare inherited disease are living much longer.
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Globe showing Asia-Pacific region

Asia recap: Innocare, Akeso in phase III; Deepseek in Antengene

Feb. 25, 2025
By Marian (YoonJee) Chu
Several Asia biotechs this week – including Innocare Pharma Ltd., Akeso Pharmaceuticals Inc., Sanbio Co. Ltd. and Ascletis Pharma Inc. – unveiled the start of new late-stage clinical trials or interim findings from early stage studies.
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Globe showing Asia-Pacific region

Asia recap: Innocare, Akeso in phase III; Deepseek in Antengene

Feb. 21, 2025
By Marian (YoonJee) Chu
Several Asia biotechs this week – including Innocare Pharma Ltd., Akeso Pharmaceuticals Inc., Sanbio Co. Ltd. and Ascletis Pharma Inc. – unveiled the start of new late-stage clinical trials or interim findings from early stage studies.
Read More
Illustration of siRNA structure
Endocrine/metabolic

Seed funding at Junevity supports siRNA therapeutics for age-related diseases

Feb. 14, 2025
Junevity Inc. has raised $10 million in seed funding to support its work creating silencing RNA (siRNA) therapeutics to address metabolic and age-related diseases, including type 2 diabetes, obesity and frailty. The seed funding will be used to enhance the company’s RESET platform and develop its first therapeutic candidates in these indications.
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Aging

University of Minnesota discovers senolytic compounds

Feb. 13, 2025
The University of Minnesota has patented flavones having senolytic activity that are described as useful for the treatment of aging and Hutchinson-Gilford progeria syndrome.
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Zebrafish
Aging

Drug screening using zebrafish wrn-KO mutant model identifies geroprotective agent

Feb. 10, 2025
Researchers from Fudan University and Southwest University published data from a study that detailed the development of a novel vertebrate model suitable for high-throughput screening of potential antiaging compounds.
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Illustration of a pink head and blue head
Neurology/psychiatric

The brain ages and survives differently in females and males

Jan. 29, 2025
By Mar de Miguel
The way the brain ages is not the same in women and men. A study in mice has observed differences in the expression of the maternal and paternal X chromosomes that could explain variation in brain aging between the sexes and a faster deterioration in some women. Another study has discovered different survival strategies in the microglial cells of females and males. Both studies highlight sex differences that could have implications for several age-related neurological disorders, such as Alzheimer’s or Parkinson’s.
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Linkgevity founders Carina Kern, CEO (left), and Serena Kern-Libera, COO (right), at the Francis Crick Institute in London
Nephrology

Linkgevity targets aging as it joins startup accelerator KQ Labs

Jan. 28, 2025
By Nuala Moran
Newco Linkgevity Ltd. has won backing from the KQ Labs accelerator program at the Francis Crick Institute in London, enabling it to take forward the lead program, an anti-necrotic drug for treating acute kidney injury, and to further develop its AI-driven system for identifying aging-related therapeutic targets. Alongside access to the Crick’s expertise in translational research and in shaping academic science to make it investible, companies joining KQ Labs receive an equity investment.
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Linkgevity founders Carina Kern, CEO (left), and Serena Kern-Libera, COO (right), at the Francis Crick Institute in London
Newco news

Linkgevity targets aging as it joins startup accelerator KQ Labs

Jan. 24, 2025
By Nuala Moran
Newco Linkgevity Ltd. has won backing from the KQ Labs accelerator program at the Francis Crick Institute in London, enabling it to take forward the lead program, an anti-necrotic drug for treating acute kidney injury, and to further develop its AI-driven system for identifying aging-related therapeutic targets.
Read More
Omniabio building

Medipost grows US, Canada base; plans US phase III of Cartistem

Jan. 21, 2025
By Marian (YoonJee) Chu
As more Asia biotechs turn to regenerative medicine to address disorders without a cure, Medipost Inc. is continuing global expansion with Cartistem, its allogeneic human umbilical cord blood-derived mesenchymal stem cell product that gained clearance in South Korea in 2012 to treat knee osteoarthritis.
Read More
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