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Home » Topics » Disease categories and therapies » Aging

Aging
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Dr. Widjaja viewing experimental data on the computer
Aging

Stop interleukin-11 to age better and live longer

July 26, 2024
By Mar de Miguel
Increased life expectancy also comes with age-related diseases. But what causes one to age? Although there is no single answer, scientists at Duke-National University of Singapore have shown in mice that interleukin-11 (IL-11) promoted aging. Blocking it improved health and lifespan.
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Dr. Widjaja viewing experimental data on the computer
Aging

Stop interleukin-11 to age better and live longer

July 24, 2024
By Mar de Miguel
Increased life expectancy also comes with age-related diseases. But what causes one to age? Although there is no single answer, scientists at Duke-National University of Singapore (NUS) have shown in mice that interleukin-11 (IL-11) promoted aging. Blocking it improved health and lifespan.
Read More
Aging

Immunopeptide supplementation restores immune function in aged mice

July 23, 2024
Age-related inflammation, also known as inflammaging, refers to low-grade chronic damage caused by increased inflammation linked to immunosenescence with impact at molecular, cellular and tissue levels. Aging amplifies the inflammatory response and increases neutrophil, monocyte and leukocyte trafficking in models of inflammation.
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Immune

Immuneage Bio launches with focus on rejuvenating the immune system by targeting HSCs

July 15, 2024
Immuneage Bio has announced its launch, with $2 million in funding and a focus on rejuvenating the immune system by targeting hematopoietic stem cells (HSCs) residing in the bone marrow.
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Alteogen’s Altos nabs ₩24.5B in series B to develop new eye drug

July 9, 2024
By Marian (YoonJee) Chu
Altos Biologics Inc., founded as an eye disease-focused subsidiary of Alteogen Inc. in 2020, raised ₩24.5 billion (US$17.7 million) in a series B financing round to advance its pipeline of therapeutics for eye-related conditions, including age-related macular degeneration (AMD). Daejeon, South Korea-based Alteogen said July 9 that the funds raised will be funneled to develop OP-01, Altos’ candidate therapy for AMD.
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Tree in the shape of human head losing leaves
Neurology/psychiatric

Anew Medical advancing Klotho gene therapy program for neurodegenerative disorders

July 9, 2024
Anew Medical Inc. has announced plans to advance its Klotho gene therapy program for neurodegenerative disorders. Initial data suggest that maintaining elevated levels of Klotho in the body significantly contributes to longer, healthier life spans, while individuals with depleted or lower than normal levels of Klotho are more susceptible to neurodegenerative disorders.
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Illustration of a senescent cell
Aging

Senescent cells are essential beyond aging

June 27, 2024
By Mar de Miguel
Senescence is a hallmark of aging, and senescent cells have a reputation to match. They are ‘zombie cells,’ sort of dead themselves but alive enough to poison their surroundings through senescence-associated secretory phenotype (SASP). The reality, though, is more complex.
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Illustration of thymus in relation to lungs and thyroid
Immune

Fibrobiologics’ artificial thymus organoid restores immune function in SCID mouse model

June 26, 2024
Fibrobiologics Inc. has announced the development of a novel artificial thymus organoid that can restore immune function in a severe combined immunodeficiency (SCID) mouse model.
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IPO puzzle pieces

China’s Ascentage drafts confidential IPO for dual listing in US

June 25, 2024
By Marian (YoonJee) Chu
Suzhou, China-headquartered Ascentage Pharma Group Corp. Ltd. has filed plans for a confidential IPO to the U.S. SEC for a potential dual listing on both the U.S. and Hong Kong stock exchanges. News of the U.S. IPO came just a few days after Ascentage drew a $75 million equity investment from Osaka, Japan-headquartered Takeda Pharmaceutical Co. Ltd. with the issuance of about 24.3 million shares at a purchase price of HK$24.09 (US$3.08) per share.
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Martin Tolar, CEO, Alzheon

Alzheon nabs $100M in series E to advance oral Alzheimer’s drug

June 20, 2024
By Marian (YoonJee) Chu
Alzheon Inc. has raised $100 million in a series E financing round to push its oral drug candidate for early Alzheimer’s disease (AD), ALZ-801 (valiltramiprosate), through a late-stage, Apolloe4 study.
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