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BioWorld - Friday, March 27, 2026
Breaking News: Trump administration impacts continue to roil the life sciences sectorBreaking News: Trump administration impacts continue to roil the life sciences sector
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US FDA finds ad introducing Wegovy pill misleading

Feb. 10, 2026
By Mari Serebrov
No Comments
Novo Nordisk A/S’ television ad introducing the tablet form of its weight-loss drug, Wegovy (semaglutide), to American consumers didn’t pass regulatory muster.
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Sava Technologies' multi-molecule biosensor technology

Sava sees positive data on microsensing tech

Feb. 10, 2026
By Shani Alexander
No Comments
Sava Technologies Ltd. reported positive clinical data showing that its multi-molecule biosensor technology can reliably monitor glucose levels beneath the skin in real time.
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Regenxbio’s MPS II gene therapy gets CRL

Feb. 10, 2026
No Comments
As many had predicted following news of a clinical hold on the gene therapy last month, Regenxbio Inc. disclosed receipt of a complete response letter (CRL) regarding its BLA for RGX-121 (clemidsogene lanparvovec) in mucopolysaccharidosis II, an ultrarare neurodegenerative disease in dire need of new therapies.
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Glass of water and tablets

Genentech plans NDA for multiple sclerosis pill with study win

Feb. 10, 2026
By Marian (YoonJee) Chu
No Comments
Genentech Inc. is covering more bases in multiple sclerosis, with its latest swing on fenebrutinib hitting a rare phase III noninferiority win against Ocrevus (ocrelizumab) in primary progressive multiple sclerosis.
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3D heart in chest

Relaxin unrest after Astrazeneca phase II HF bid joins failures

Feb. 10, 2026
By Randy Osborne
No Comments
Wall Street pushback against relaxin player Tectonic Therapeutic Inc. was sharp, but a trial design that differs could save the drug from the fate of Astrazeneca plc’s long-acting relaxin-2 analogue, AZD-3427, which the pharma giant has “removed from phase II,” where it was being tested in a trial called Re-phire, because of less than ideal efficacy.
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Woman itching wrist

Evommune, Nektar soar on atopic dermatitis phase II data

Feb. 10, 2026
By Karen Carey
No Comments
Marking an important day for those with atopic dermatitis, shares of two biopharmas surged on clinical data suggesting new biologics are on their way to help address 40% of patients with uncontrolled disease.
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Evommune, Nektar soar on atopic dermatitis phase II data

Feb. 10, 2026
No Comments
A preview of the next edition of BioWorld, Feb. 10, 2026
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Photomicrograph of hepatocellular carcinoma
Cancer

ATF6 shapes liver cancer: from ER stress to inflammation

Feb. 10, 2026
By Coia Dulsat
No Comments
Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer, representing approximately 75-85% of all cases. Often considered preventable, primary liver cancer ranks as the sixth most frequently diagnosed cancer and the third leading cause of cancer deaths worldwide. Through a multi-institutional effort, researchers have identified activated ATF6α as a driver of HCC that suppresses immune defenses, predicts response to immune checkpoint therapy, and represents a potential target for intervention.
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White currency symbols on white background

Global investors optimistic about med-tech exits in 2026

Feb. 9, 2026
By Shani Alexander
No Comments
Global investors in med tech are confident about exit opportunities in the year ahead. The strategics have already started making acquisitions, the IPO window – which reopened last year – is expected to remain active, and the investment firms have companies in their portfolios that are well-positioned for exit. With fundamentals in the sector still robust, 2026 is expected to reward companies that deliver clear clinical value.
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Regulatory actions for Feb. 9, 2026

Feb. 9, 2026
Regulatory snapshots for biopharma and med tech, including global submissions and approvals, and other regulatory decisions and designations: Akeso, Everest, GSK, Kelun-Biotech, Kite, Neurophet, P+F Products and Features, Partner Therapeutics, Pfizer, Spinal Resources, Zimmer Biomet.
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