Scientists at Duke University School of Medicine in Durham, N.C., have developed a small-molecule inhibitor of the cellular stress-protective transcription factor, heat-shock factor 1, which showed developmental promise against treatment-resistant prostate cancer and other cancers. The small molecule, Direct Targeted HSF1 InhiBitor (DTHIB), may also be a useful research tool for investigating the regulation and role of HSF1 in basic stress biology and in cancer.
Keeping you up to date on recent developments in oncology, including: Microscopic robots inch closer to clinical practicability; One thing often leads to another for cancer patients; PARP inhibitors under more scrutiny; New liposome may suppress false positives in FDG-PET.
Keeping you up to date on recent developments in cardiology, including: Differences seen between the sexes in terms of stroke survival; Light used to control cardiac waves; 3D-printed blood vessels ID possible link between coronavirus, stroke.
HONG KONG – A research team at the Chinese University of Hong Kong (CUHK) has developed a fully automated, low-cost and rapid microrobotic diagnostic system that can be used with multiple pathogens, including COVID-19. The system works by integrating fluorescent microrobots with an external magnetic actuation system to detect pathogens in patient samples.
Keeping you up to date on recent developments in orthopedics, including: Remote monitoring leads to fourfold decline in returns to hospital after joint surgery; Researchers identify rare genetic bone disorder through massive sequencing methods; Orthogrid Systems says data support the use of its technology for orthopedic surgery; Exercise may protect bone health after weight loss surgery.
Keeping you up to date on recent developments in oncology, including: Multicancer screening paradigm bolstered in new study; Potentiating PARP inhibitors; New non-viral vector siRNA approach described; NICE nods to combo therapy for HCC.
Keeping you up to date on recent developments in cardiology, including: Biomarkers can forecast the development of incident heart failure; Mouse model helps researchers find MAARS lncRNA; Heart disease deaths rise in age of COVID-19.
Researchers at Thomas Jefferson University have found that using ultrasound to pop microbubbles already present in a contrast agent nearly doubled liver tumor response to transarterial radioembolization. The procedure raised no safety concerns and increased the likelihood of patients receiving a liver transplant.
PERTH, Australia – Researchers at the QIMR Berghofer Medical Research Institute in Queensland have developed a way of testing whether COVID-19 patients’ immune systems are gearing up to fight the virus that causes the disease.
Keeping you up to date on recent developments in neurology, including: Research suggests SARS-CoV-2 enters the brain; Technique developed to predict seizures; Machine intelligence improves brain mapping research; Hearing, blood sugar linked to cognitive function among older Latinos.
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