KRAS is the most frequently mutated oncogene in solid tumors in general, and in lung tumors in particular. There are more patients whose lung tumors are driven by KRAS mutations than by ALK, Ros, Ret and TRK alterations. Combined. And after 40 years, they look to be getting a targeted therapy, or even two.
Keeping you up to date on recent developments in oncology, including: Less fractionation, fewer trips not a problem for some high-risk prostate cancers; PCOS passed on in the epigenes; Algorithm uses ultrasound images for classification.
Keeping you up to date on recent developments in cardiology, including: Radial access shows well in analysis of PCI data; ACC, SVS combine registries; VAD-associated ED visits down, but room for improvement.
Keeping you up to date on recent developments in neurology, including: Smartwatch sensors enable remote monitoring, treatment guidance for Parkinson’s patients; Imaging of a living brain can help differentiate dementia; Morphine itch comes from neurons, not mast cells.
Keeping you up to date on recent developments in diagnostics, including: A deep learning tool to predict cardiovascular risk; Smartphone-based COVID-19 test; PCOS passed on in the epigenes.
Keeping you up to date on recent developments in orthopedics, including: Blood pressure can be controlled without drugs after spinal cord injury; Researchers develop technique to replicate bone-remodeling processes; New technique to fast-track pain research.
Keeping you up to date on recent developments in oncology, including: New nanotech approach to skin cancer in development at Yale; Imaging for prediction of response to hormone therapy; Algorithm is predictive of response to immunotherapy.
Keeping you up to date on recent developments in cardiology, including: Registry data suggest invasive procedures may be omitted in some cardiac arrest patients; Cryoablation beats medical management for some AF patients; Aetna deems certain leadless pacing experimental.
The Human Skin Cell Atlas, comprising transcriptomes of 528,253 single cells, shows that cellular processes involved in skin development in embryos are reactivated in inflammatory skin diseases. In addition to suggesting potential new drug targets for atopic dermatitis and psoriasis, the transcriptomes provide a new route to understanding other inflammatory diseases, and provide a template for culturing skin for wound repair, according to the authors of a paper published in the Jan. 22, 2021, issue of Science.
Keeping you up to date on recent developments in neurology, including: Genetic analysis of symptoms yields new insights into PTSD; AI used to predict schizophrenia in relatives of patients; Growth factors linked to lysosomes, Parkinson’s risk; Study links ALS gene to tumor suppressor, transcription changes.
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