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BioWorld Asia
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In the clinic for Dec. 14-20, 2021

Dec. 21, 2021
Clinical updates from Asia, including trial initiations, enrollment status and data readouts and publications: 60 Degrees, Acelyrin, Arcturus, Axcella, Capricor, Douglas, Eiger, Eucure, Geovax, Glaxosmithkline, HDT, Jiangsu Hengrui, Inmagene, Merck, Nicox, Novaliq, Nrx, Nykode, Pfizer, Recce, Ridgeback, Sanofi, Valneva.
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Financings for Dec. 21, 2021

Dec. 21, 2021
Biopharmas in Asia-Pacific raising money in public or private financings: Beroni, Bionomics, Cargene, Propanc.
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Conference data for Dec. 14-16, 2021: ASH

Dec. 21, 2021
Data presented at the American Society of Hematology annual meeting, including: Antengene, Aptose, Ascentage, Beigene, Daiichi Sankyo, Hutchmed, I-Mab, Iaso, Innocare, Innovent, JW, Tessa.
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Appointments and advancements for Dec. 21, 2021

Dec. 21, 2021
New hires and promotions in the biopharma industry in Asia-Pacific, including: I-Mab, Transcenta, Universe.
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US SEC: More risk disclosure needed from China-based companies

Dec. 21, 2021
By Mari Serebrov
Citing recent events that highlighted the risks of investing in companies based in China or that have the majority of their operations there, the U.S. SEC’s Division of Corporation Finance is seeking more specific disclosures from those companies about the legal and operational risks of investing in their securities.
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Biosion licenses out anti-Trop2 humanized MAb to Obi Pharma

Dec. 21, 2021
By Doris Yu
Obi Pharma Inc. has acquired global rights to BSI-04702, an anti-trophoblast antigen 2 (Trop2) humanized monoclonal antibody (MAb), from Biosion Inc. Obi is granted exclusive rights for further preclinical and clinical development, registration and commercialization of the candidate as an antibody-drug conjugate and other derivative products.
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Chinese flag and pills

China prioritizing rare disease drugs

Dec. 21, 2021
By Mari Serebrov
China is making some advances in approving and reimbursing drugs to treat or prevent rare diseases. More than 60 rare disease drugs have been approved for marketing in China, with more than 40 of those included in the national medical insurance system, according to figures released at a national conference on rare diseases held in Beijing Dec. 18.
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Mesoblast shares depressed by Novartis deal termination

Dec. 21, 2021
By Tamra Sami
PERTH, Australia – It’s been a year that Mesoblast Ltd. might like to forget. The company’s stock dropped 17% Dec. 15 on the news that Novartis AG will terminate its licensing agreement with Mesoblast for remestemcel-L.
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Providence and Everest’s vaccine is first mRNA in WHO’s Solidarity Trial Vaccines study

Dec. 21, 2021
By David Ho
Everest Medicines Ltd. and Providence Therapeutics Holdings Inc.’s COVID-19 vaccine was cleared for inclusion in the World Health Organization’s (WHO) Solidarity Trial Vaccines clinical trial.
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Handshake with digital globe overlay

Qilu in-licenses HBV-focused RNAi therapy from Arbutus in $300M deal

Dec. 21, 2021
By Doris Yu
Qilu Pharmaceutical Co. Ltd. licensed rights to AB-729, an RNA interference (RNAi) therapeutic from Arbutus Biopharma Corp., in a deal worth up to $300 million. Qilu obtained rights to develop and commercialize the phase II asset for the treatment of hepatitis B (HBV) in mainland China, Hong Kong, Macau, and Taiwan. Under terms of the agreement, Qilu will pay Arbutus $40 million up front, as well as up to $245 million in development, regulatory and sales milestones. In addition, Qilu will make a $15 million equity investment in Arbutus at a price of $4.19 per share.
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