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BioWorld - Sunday, July 12, 2026
Home » Authors » Brian Orelli

Articles by Brian Orelli

When tech and health merge, how will life sciences prevail?

March 22, 2018
By Brian Orelli

TCR2 lands $125M series B to advance modified T-cell therapies

March 22, 2018
By Brian Orelli
Coming off a $44.5 million series A financing in late 2016, TCR2 Therapeutics Inc. snagged another $125 million in an oversubscribed series B financing to advance programs using its T-Cell Receptor Fusion Construct (TRuC) platform. (See BioWorld Today, Dec. 9, 2016.)
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Regeneron sees more growth ahead with Eylea

March 20, 2018
By Brian Orelli
Like drugmakers are apt to do, Regeneron Pharmaceuticals Inc. is looking upstream of its current indications to capture additional patients for its anti-VEGF eye drug, Eylea (aflibercept), but not every analyst is convinced an additional indication will result in sustainably increased sales.
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When tech and health merge, how will life sciences prevail?

March 19, 2018
By Brian Orelli
The line between health care and technology is becoming blurred.
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AACR previews meeting with data on CAR T and HER2

March 16, 2018
By Brian Orelli
As 22,000 participants prepare to descend on Chicago next month for the American Association for Cancer Research (AACR) 2018 meeting, the organization released many of the abstracts for presentations. Unfortunately, as Evercore ISI analyst Umer Raffat wrote in a note to clients, "Most abstracts of significance are all embargoed."
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Early involvement from pricing team can pay off down the line

March 12, 2018
By Brian Orelli
A new report by strategy and marketing consultants Simon-Kucher & Partners found that drug companies that involve their pricing and market access (P&MA) teams early in the development of drugs appear to be the most profitable.
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Looking to 'Prevail' against Parkinson's with gene therapy

March 9, 2018
By Brian Orelli
Going after neurodegenerative diseases where lysosomal dysfunction is an underlying cause, Prevail Therapeutics Inc. announced a $75 million series A round to fund development of its gene therapies.
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Blockchain building out in the drug industry

Feb. 26, 2018
By Brian Orelli
Blockchain, the transaction-following technology that got its fame as a way to follow the movements of cryptocurrencies such as Bitcoin, is making its way into the pharmaceutical industry, proving its potential uses are far-flung.
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Blockchain building out in the drug industry

Feb. 26, 2018
By Brian Orelli
Blockchain, the transaction-following technology that got its fame as a way to follow the movements of cryptocurrencies such as Bitcoin, is making its way into the pharmaceutical industry, proving its potential uses are far-flung.
Read More

Sleeper data: Early stage efficacy, plus plenty of genes to explore

Feb. 12, 2018
By Brian Orelli
Despite being the second most prevalent mental disorder with a third of the general population reporting insomnia complaints and 10 percent meeting the strict definition of insomnia disorder, the treatment options for the disease are lacking. Considering that many treatments lead to tolerance and dependence and the potential for morning sedation, drugs using new mechanisms of action are sorely needed.
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