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BioWorld - Saturday, December 20, 2025
Home » Authors » John Fox

Articles by John Fox

Circular RNA promotes colon cancer growth and metastasis

March 15, 2017
By John Fox
The results of a new Taiwanese study into the little known role of circular RNA (circRNA) in colorectal cancer (CRC) pathogenesis suggest a new approach is needed to treatment of the cancer, in which therapy should not only target proteins, but also non-protein coding RNAs.
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Circular RNA promotes colon cancer growth and metastasis

March 14, 2017
By John Fox
The results of a new Taiwanese study into the little known role of circular RNA (circRNA) in colorectal cancer (CRC) pathogenesis suggest a new approach is needed to treatment of the cancer, in which therapy should not only target proteins, but also non-protein coding RNAs.
Read More

Dual MAb therapy targets CSCs, prevents resistance

March 13, 2017
By John Fox
Combining two monoclonal antibody (MAb) cancer therapies as one treatment not only shrank bulk tumors, but also targeted the cancer stem cells (CSCs) that can be responsible for disease relapse, according to a new Chinese study reported in the March 8, 2017, edition of Science Translational Medicine.
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Specific lead identified in the fight against TB

March 8, 2017
By John Fox
Novel analogues of a class of antibacterial compounds isolated from soil bacteria could lead to the development of urgently needed new treatments for tuberculosis (TB), according to the findings of a study led by Australian researchers at the University of Sydney.
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Specific lead identified in the fight against TB

March 7, 2017
By John Fox
Novel analogues of a class of antibacterial compounds isolated from soil bacteria could lead to the development of urgently needed new treatments for tuberculosis (TB), according to the findings of a study led by Australian researchers at the University of Sydney.
Read More

Targeting apoptosis regulator ameliorates NASH in mice, primates

March 1, 2017
By John Fox
A study by Chinese researchers has identified a key suppressor of apoptosis in nonalcoholic steatohepatitis (NASH), and then showed that a small peptide segment derived from it ameliorated the currently untreatable liver disease in mice and nonhuman primates.
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Potential drug target found for Chikungunya virus arthritis

March 1, 2017
By John Fox
A specific immune system proteinase, granzyme A, was shown to promote arthritic inflammation in mice infected with chikungunya virus (CHIKV), in an Australian study reported in the Feb. 16, 2017, edition of PLOS Pathogens.
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Targeting apoptosis regulator ameliorates NASH in mice, primates

March 1, 2017
By John Fox
A study by Chinese researchers has identified a key suppressor of apoptosis in nonalcoholic steatohepatitis (NASH), and then showed that a small peptide segment derived from it ameliorated the currently untreatable liver disease in mice and nonhuman primates.
Read More

Potential drug target found for Chikungunya virus arthritis

Feb. 23, 2017
By John Fox
A specific immune system proteinase, granzyme A, was shown to promote arthritic inflammation in mice infected with chikungunya virus (CHIKV), in an Australian study reported in the Feb. 16, 2017, edition of PLOS Pathogens.
Read More

Bacterial immunotherapy shows promise in tumor-targeting

Feb. 16, 2017
By John Fox
A nonvirulent tumor-targeting bacterial strain bioengineered to release multiple Toll-like receptor (TLR) ligands was shown to suppress tumor growth and prolong survival in mouse tumor models in a Korean study, suggesting it could be a new cancer immunotherapy in humans.
Read More
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