A Japanese study has demonstrated a new management approach for fetuses with myelomeningocele (MMC), one of the most severe forms of spina bifida, employing 3-D skin reconstructed using induced pluripotent stem cells (iPSCs) derived from maternal amniotic fluid cells (AFCs).
Therapeutic targeting of endosomal GTP-binding (G protein)-coupled receptors (GPCRs) is a novel means of drug delivery that may offer more effective and selective treatment for chronic pain and possibly other conditions, a study by Australian researchers at Monash University in Melbourne has concluded.
A new study by Japanese researchers has shown how the loss of a key mitochondrial protein facilitates progression of Parkinson's disease (PD), identifying a new therapeutic target and hence the potential for the discovery and development of new PD treatments.
Therapeutic targeting of endosomal GTP-binding (G protein)-coupled receptors (GPCRs) is a novel means of drug delivery that may offer more effective and selective treatment for chronic pain and possibly other conditions, a study by Australian researchers at Monash University in Melbourne has concluded.
A new Chinese study's findings suggest Adriamycin-based chemotherapy may simulate cancer stem cells (CSCs) through transcription factor signaling activation, but that such signaling is inhibited by statins. Reported in the May 25, 2017, online edition of Stem Cell Reports, the results may be important in designing new osteosarcoma treatment regimens.
A new Chinese study’s findings suggest Adriamycin-based chemotherapy may simulate cancer stem cells (CSCs) through transcription factor signaling activation, but that such signaling is inhibited by statins. Reported in the May 25, 2017, online edition of Stem Cell Reports, the results may be important in designing new osteosarcoma treatment regimens.
Japanese researchers have screened existing drugs for potential to treat amyotrophic lateral sclerosis (ALS) using neurons developed from induced pluripotent stem (iPS) cells of a patient with an ALS gene mutation, thereby identifying a potential new target pathway for drugs against the currently incurable disease.
Japanese researchers have screened existing drugs for potential to treat amyotrophic lateral sclerosis (ALS) using neurons developed from induced pluripotent stem (iPS) cells of a patient with an ALS gene mutation, thereby identifying a potential new target pathway for drugs against the currently incurable disease.
