Scientists at the University of Tuebingen have identified a network of antifibrotic RNAs, and showed that this network was controlled by the transcription factor Pparg. Fibrosis, which is essentially the formation of inappropriate scar tissue, contributes to multiple diseases, and its molecular mechanisms are poorly understood.
Scientists from the Wellcome Trust Sanger Institute have shown that antioxidant treatment could reverse the competitive advantage of p53-mutated cells in the esophagus of transgenic mice.
A team at Dartmouth University has shown that in fruit flies, stressful experiences could lead to epigenetic changes that led to a preference for ethanol-rich foods for several generation of offspring.
Despite its rather specific name, macrophage migration inhibitory factor (MIF) has multiple roles. One of those roles is to serve as a chaperone protein that helps the proper folding of superoxide dismutase (SOD1).
Scientists from the University of Cambridge have reported that a high proportion of methicillin-resistant Staphylococcus aureus (MRSA) strains were resistant to penicillin-class antibiotics, the beta-lactams, when they were treated with a combination of penicillins and beta-lactamase inhibitors.
