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Home » Newsletters » BioWorld

BioWorld

April 11, 2019

View Archived Issues

Long-term solutions, not bandages, needed to make insulin affordable

As Congress continues to scrutinize the rising cost of insulin, two insulin producers and a pharmacy benefit manager (PBM) scrambled to put their best side in the spotlight. Read More

Inozyme raises $67M in series A2 financing

Cambridge, Mass.-based Inozyme Pharma Inc. just added $67 million to its financing with a series A2 boost led by Pivotal Bioventure Partners and Sofinnova Investments. Read More

Curing hepatitis B difficult, but not impossible; I-O set the precedent, panelists say

VIENNA – Current FDA-approved options for patients infected with the hepatitis B virus (HBV) consist of immunomodulators, and nucleoside and nucleotide analogues, all of which target chronic disease and suppress virus replication, but do not cure HBV and leave no options for acute patients. Read More

Beigene, Bioatla combining I-O candidates in co-development agreement worth up to $269M

HONG KONG – Commercial-stage biotech company Beigene Ltd. and clinical-stage company Bioatla LLC agreed to co-develop and bring to the market BA-3071, an investigational CAB CTLA4 antibody, as a monotherapy and in combination with Beigene's investigational anti-PD-1 antibody, tislelizumab, to treat cancer. Read More

Just a small one: Avectas raises $10M for alcohol-based gene transfer technology

DUBLIN – Avectas Ltd. raised $10 million in equity finance to fund the scale-up, validation and commercialization of its virus-free gene transfer technology.  Read More

Azitra advances Netherton program with new SBIR grant

Azitra Inc., a Connecticut-based startup working on a bacteria-based therapy for the rare genetic skin condition Netherton syndrome (NS), has been awarded a $719,700 SBIR grant to advance development of its lead candidate, AZT-02.  Read More

Financings

Phasebio Pharmaceuticals Inc., of Malvern, Pa., said it has begun an underwritten public offering of 3 million shares of its common stock and expects to grant the underwriters a 30-day option to purchase up to an additional 450,000 shares of common stock at the public offering price. Read More

Regulatory front

A U.S. federal grand jury indicted Indivior Inc., formerly Reckitt Benckiser Pharmaceuticals Inc., and Indivior plc on one count of health care fraud, four counts of mail fraud and 22 counts of wire fraud related to the company's marketing of Suboxone Film (buprenorphine) as a treatment of opioid addiction.  Read More

Other news to note

Alligator Bioscience AB, of Lund, Sweden, said preclinical data showed that ATOR-1015 physically localizes to the tumor in an experimental tumor model using a live imaging computerized technique. Alligator said the data, presented at the Essential Protein Engineering Summit in Boston, reinforce the concept that its wholly owned CTLA4 bispecific antibody selectively activates the immune system in the tumor area. Read More

Appointments and advancements

Kaleido Biosciences Inc., of Lexington, Mass., appointed Johan van Hylckama Vlieg chief scientific officer and Clare Fisher chief business officer. Read More

Clinical data for April 10, 2019

Read More

Regulatory actions for April 10, 2019

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