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BioWorld - Monday, June 5, 2023

Cell therapy

Home » Topics » Drugs » Cell therapy
  • T cells attack cancer cells
    June 2, 2023

    Medigene expands pipeline into neoantigens with programs targeting KRAS mutations and HLAs

    Medigene AG has announced its pipeline expansion into neoantigens with KRAS as the first target in its MDG-10xx program, a T-cell receptor engineered T cell (TCR-T) therapy being developed in combination with the company's PD1-41BB switch receptor technology.
  • Mesenchymal stem cell msc
    May 29, 2023

    Optimized mesenchymal stem cell therapy exhibits efficacy in preclinical model of pulmonary hemorrhage

    The targeted delivery of optimized stem cells directly into injured tissues has been used to maximize efficacy and minimize systemic exposure. Still, despite hundreds of clinical trials evaluating mesenchymal stem cell (MSC) therapy as a treatment, clinical efficacy remains highly variable. Investigators at Case Western Reserve University have developed an optimized combination of cytokines and growth factors applied to MSCs (HXB-319).
  • Human nk cell
    May 29, 2023

    HLCN-061 demonstrates enhanced persistence, migration and cytotoxicity in preclinical models

    Researchers from Healios K.K. presented preclinical data for HLCN-061, a novel gene-engineered human induced pluripotent stem cell (iPSC)-derived NK cell product being developed for the treatment of solid tumors.
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