Endevica Bio Inc. has disclosed cyclic peptides acting as melanocortin MC1 and/or MC5 and/or MC3 and/or MC4 receptor agonists. They are reported to be useful for the treatment of substance abuse and dependence and diabetes.
Counterx Therapeutics Inc. has executed an exclusive licensing agreement with the University of Minnesota and the University of Washington for a portfolio of novel monoclonal antibody and vaccine candidates targeting fentanyl and opioid overdose.
Opioid use disorder (OUD) causes high morbidity and mortality rates, with fentanyl driving unprecedented overdose rates. Researchers from the University of California have used an AI-based drug discovery platform with the aim of identifying preclinical drug candidates for OUD.
