Company*
(Country;
Symbol)

Company*
(Country;
Symbol)

Product

Terms/Details (Date)


Althea
Technologies
Inc.*

Altus Pharmaceuticals Inc. (ALTU)

Althea will manufacture materials for Phase III trials of Altus' ALTU-238

The product is a crystallized formulation of human growth hormone; terms of the contract were not disclosed (8/22)

Carna
Biosciences
Inc.*
(Japan)

Bio-Connect BV* (the Netherlands) and KinaseDetect ApS* (Denmark)

The companies entered agreements for distribution of protein kinases from Carna

Bio-Connect got rights in much of Western Europe, while KinaseDetect got rights in Scandinavia (8/4)

Isis
Pharmaceuticals
Inc.
(ISIS)

Bruker Daltonics Inc. (unit of Bruker Biosciences Corp; BRKR)

Deal covering the manufacturing and distribution of Isis' Ibis T5000 biosensor system

Bruker will be the worldwide manufacturer of the system, which is used to identify infectious organisms in a sample, and will sell it in much of the world (7/31)

Omnia
Biologics Inc.*

Potentia Pharmaceuticals Inc.*

Deal under which Omnia will provide Potentia cGMP manufacturing services

Terms of the master services agreement were not disclosed (8/8)

Phyton Biotech
Inc.
(affiliate
of DFB
Pharmaceuticals
Inc.*)

Insmed Inc. (INSM)

Phyton will use its plant cell fermentation technology to develop a manufacturing process for Insmed's iPlex product

The process could be used to meet future demand of the product, which is approved to treat growth failure in children with severe primary IGF-1 deficiency (7/31)

Valentis Inc.
(VLTS)

Cobra Biologics Ltd (UK; AIM:CBF)

Cobra acquired certain biomanufacturing rights and intellectual property

Valentis, which was downsizing following a Phase IIb trial failure, gets an undisclosed payment in the deal (8/7)

XOMA Ltd.
(XOMA)

AVEO Pharmaceuticals Inc.*

XOMA will manufacture the anti-HGF antibody AV-299 in support of early clinical trials

The deal is worth $6M to XOMA, which earlier humanized the antibody (9/28)


Notes:

* Private companies are indicated with an asterisk.

# Item occurred before the time frame of this chart but was not included in the previous chart.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

AIM = Alternative Investment Market.