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BioWorld - Sunday, January 18, 2026
Home
» 1999 Price Performance Of Biotechnology Stocks Ranked By Percent Change In Closing Price From 1998 Year-End (Or IPO Price For 1999 IPOs)
1999 Price Performance Of Biotechnology Stocks Ranked By Percent Change In Closing Price From 1998 Year-End (Or IPO Price For 1999 IPOs)
Jan. 1, 2000
STOCKS THAT LOST VALUE
Company Name
Symbol
12/31/98
12/31/99
%YTD
Icos
ICOS
29.75
29.25
-2
Micrologix Biotec
MBI*
2.7
2.65
-2
Genetronics
GEB
3.312
3.25
-2
Igen
IGEN
30.625
29.75
-3
Cellegy Pharma
CLGY
3.5
3.375
-4
Adv Tissue Sci
ATIS
2.593
2.5
-4
Atlantic Pharma
ATLC
1.5
1.438
-4
Allelix
AXB*
4.19
4
-5
Cortech
CRTQ
6.219
5.875
-6
Neurogen
NRGN
17.5
16.5
-6
XOMA
XOMA
3.187
3
-6
Carrington
CARN
2.125
2
-6
Triangle Pharma
VIRS
13.625
12.813
-6
Synbiotics
SBIO
2.562
2.406
-6
CytRx
CYTR
0.968
0.906
-6
Genzyme
GENZ
49.75
45
-10
BioMarin
BMRN
13
11.75
-10
Northfield Labs
NFLD
12.375
11.063
-11
AltaRex
AXO*
0.46
0.4
-13
GalaGen
GGEN
2.156
1.813
-16
Agritope
AGTO
1.312
1.094
-17
Organogenesis
ORG
11
8.688
-21
Liposome Co
LIPO
15.437
12.188
-21
Synsorb Biotech
SYBB
2.375
1.875
-21
Diagnostic Prod
DP
31.125
24.5
-21
Biomune Sys
BIME
1.688
1.313
-22
British Biotech
BBIOY
5.875
4.5
-23
DepoMed
DMI
7.875
6
-24
Aradigm
ARDM
12.5
9.5
-24
Biochem Pharma
BCHE
28.625
21.75
-24
Coulter Pharma
CLTR
30
22.688
-24
Ecogen
EECN
1.687
1.25
-26
Bioreliance
BREL
8
5.719
-29
Biora AB
BIORY
13
9
-31
Axys Pharma
AXPH
5.875
4.063
-31
Genset
GENXY
27.625
19.063
-31
Vysis
VYSI
5.375
3.625
-33
Alza
AZA
52.25
34.625
-34
Biomatrix
BXM
29.125
19.25
-34
UroCor
UCOR
6.375
4.188
-34
Transgene
TRGNY
15.375
10
-35
Anesta
NSTA
26.625
17.188
-35
Adv Poly Sys
APOS
5.375
3.438
-36
Aquila Biopharma
AQLA
3.875
2.375
-39
Aviron
AVIR
25.875
15.813
-39
Palatin Tech
PLTN
4.125
2.5
-39
Cypress Bio
CYPB
3
1.813
-40
Phoenix Intl
PHX*
17
10.25
-40
Idexx Labs
IDXX
26.906
16.125
-40
Atrix Labs
ATRX
8.875
5.188
-42
Ortec Int'l
ORTC
13.125
7.5
-43
Magainin
MAGN
3.187
1.813
-43
GelTex
GELX
22.625
12.813
-43
Adv Magnetics
AVM
7.312
4.125
-44
La Jolla Pharm
LJPC
4.5
2.531
-44
Oxis Int'l
OXIS
2.875
1.594
-45
Gliatech
GLIA
30
16.625
-45
Biotime
BTIM
17.375
8.875
-49
Icon plc
ICLR
33.5
17
-49
North Am Vacc
NVX
8.875
4.5
-49
MacroChem
MCHM
8.437
4.188
-50
Calypte Biomed
CALY
2.875
1.406
-51
Techniclone Int'l
TCLN
1.093
0.531
-51
Flamel Tech
FLMLY
4.375
2.125
-51
Isis Pharm
ISIP
12.937
6.25
-52
Parexel Intl
PRXL
25
11.813
-53
ImmuLogic
IMUL
1.218
0.563
-54
Synaptic Pharma
SNAP
15
6.75
-55
Osteotech
OSTE
31
13.375
-57
Algos Pharma
ALGO
26
11
-58
Cell Pathways
CLPA
22
9.25
-58
Draxis Health
DRAXF
2.859
1.188
-58
Scios
SCIO
10.375
4.188
-60
Immune Resp
IMNR
10.875
4.344
-60
Pharma Prod Devlp
PPDI
30.062
11.875
-60
Cypros Pharma
CYP
3.25
1.25
-62
Questcor Pharm
QSC
3.25
1.25
-62
Sonus Pharma
SNUS
6.75
2.5
-63
PathoGenesis
PGNS
58
21.438
-63
AutoImmune
AIMM
2.25
0.813
-64
Quintiles
QTRN
53.375
18.688
-65
Molecular Bio
MB
2.937
1
-66
Aastrom Biosci
ASTM
2.875
0.781
-73
Zonagen
ZONA
19.125
4.375
-77
Incara Pharma
INCR
9
1.5
-83
Note: *Stock trades on a Canadian exchange.
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1999 Price Performance Of Biotechnology Stocks Ranked By Percent Change In Closing Price From 1998 Year-End (Or IPO Price For 1999 IPOs)
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