Business is shaky, but science is groundbreaking for engineered T-cell study

Nov. 11, 2022

In August, Pact Pharma Inc. suspended its phase I trial after 16 patients had been treated with its autologous CRISPR-edited T cells “for business reasons,” the company announced at the time. Scientifically, though, the trial broke enough new ground to be concurrently presented in a late-breaking oral session at the 2022 annual meeting of the Society for the Immunotherapy of Cancer (SITC) and published as an accelerated article preview in Nature on Nov. 10, 2022.

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SCAN is core circuit affected in Parkinson’s disease

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First-in-class pan-inflammasome blocker for hidradenitis suppurativa

BioWorld Science

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RX-10616 improves radiotherapy efficacy in HNSCC

BioWorld Science

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CROI 2026: Neurodegeneration, the challenge of aging with HIV

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Antiretroviral therapies against HIV have been in use for more than 30 years and have enabled people living with HIV to maintain undetectable viral levels. Many...