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Home » Reduced RNA editing reveals mitochondrial dysfunction in schizophrenia
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Neurology/Psychiatric

Reduced RNA editing reveals mitochondrial dysfunction in schizophrenia

April 11, 2023
By Mar de Miguel
RNA editing in schizophrenia (SCZ)-associated genes was decreased in postmortem brains of individuals of European descent, according to a study from the University of California, Los Angeles (UCLA). The scientists obtained the RNA editome from SCZ brains to detect the sequence changes in their RNA and observed hypoediting in noncoding regions related to mitochondrial function, such as the mitofusin-1 (MFN1) gene.
BioWorld Science Medical technology RNA Proteomics Neurology/psychiatric

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