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BioWorld - Saturday, February 4, 2023

Proteomics

Home » Topics » Omics » Proteomics
  • Muscle anatomy illustration of man running
    Jan. 24, 2023
    By Anette Breindl

    New method enables much more detailed look at exerkines, secreted proteins

    Researchers at the Dana-Farber Cancer Institute have been able to identify proteins that were released from muscles during exercise in relatively small quantities. Using their method, the team was able to demonstrate that the neurotrophic factor prosaposin was produced during exercise. Prosaposin is “a well-known CNS neurotrophic factor, but has never been seen to come out of muscle or fat,” Bruce Spiegelman told BioWorld. Spiegelman is a researcher at the Dana-Farber Cancer Institute and Stanley J. Korsmeyer Professor of Cell Biology and Medicine at Harvard Medical School.
  • Nitrosylation hero
    Dec. 19, 2022
    By Mar de Miguel

    Nitric oxide-modified proteins reveal sex differences in Alzheimer’s

    Alzheimer’s disease has a higher incidence in women. This sex difference was associated with a modification of certain proteins of the immune system. According to a recent study, the drop in estrogen with menopause increased the expression in the brain of a neurotransmitter, nitric oxide (NO), generating the S-nitrosylation of complement factor C3 (abbreviated SNO-C3), which activated the microglia.
  • 12 08 nomic bio
    Dec. 8, 2021
    By Meg Bryant

    Nomic in $17M series A funding for high-throughput proteomic platform

    Protein profiling startup Nomic Bio has secured $17 million in an oversubscribed series A financing led by Lux Capital. The funds will be used to expand the company’s servicing and manufacturing labs in Montreal and Boston, to broaden access to its proteomic platform by scaling profiling capacity to 100,000 samples per quarter starting in the second quarter of 2022 and by scaling its protein-detection method, called nELISA, to 500 on-boarded proteins.
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Authors

  • Annette Boyle
  • Meg Bryant
  • Nuala Moran
  • Catherine Longworth
  • Mar de Miguel
  • Anette Breindl
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