Roche and Icagen patent new Kv7.2 activators

June 15, 2023

Researchers from F. Hoffmann-La Roche Ltd., Hoffmann-La Roche Inc. and Icagen Inc. have disclosed heteroaryl-urea compounds acting as potassium voltage-gated channel subfamily KQT member 2 (KCNQ2; Kv7.2) activators reported to be useful for the treatment of autism spectrum...

BioWorld Science Neurology/psychiatric Patents

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CROI 2026: Neurodegeneration, the challenge of aging with HIV

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Antiretroviral therapies against HIV have been in use for more than 30 years and have enabled people living with HIV to maintain undetectable viral levels. Many...

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CROI 2026 highlights depression and cognitive vulnerability in HIV

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The effects of aging pose an additional challenge for people with HIV due to the neurological and psychological consequences that persist despite antiretroviral...

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University of Southern California reports new MAPT aggregation inhibitors

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The University of Southern California has identified (2-oxo-2H-chromen-3-yl) scaffold-based carboxamide analogues acting as potent microtubule-associated protein...