HONG KONG – D3 Bio Inc. is the new kid on the biopharma block in Shanghai, kicking off with a $200 million series A financing backed by some of Asia’s most prominent venture capital firms.
Detailed research over the past decade has shown that that the protein stimulator of interferon genes (STING) is a master regulator of type I interferons and as such plays an essential role in activating innate immunity. STING’s importance in orchestrating the body’s response to pathogenic, tumor, or self-DNA in the cytoplasm has made it a hot target in immunology research and drug discovery and several biopharma companies have started programs dedicated to this area spanning infectious and inflammatory diseases as well as cancer.
Much of the research on the immune response in patients with COVID-19 has focused on the humoral antibody response. Adaptive Biotechnologies Corp., on the other hand, has focused on cellular immunity to measure the T-cell response to infection with SARS-CoV-2.
Not only did newly emergent Kyverna Therapeutics Inc. burst out of the gate with a $25 million series A, but it enhanced its entrance with a deal from Gilead Sciences Inc., one of the company’s initial funders, potentially worth $587.5 million.
DUBLIN – Truffle Capital closed off its fifth Biomedtech fund with a €250 million (US$279 million) raise, which it will deploy in about a dozen companies located mainly in France. The fund took a little longer to close than originally planned but it is significantly larger than it had originally intended. “Our initial objective was €200 million,” Truffle Capital CEO and co-founder Philippe Pouletty told BioWorld MedTech.
DUBLIN – Truffle Capital closed off its fifth Biomedtech fund with a €250 million (US$279 million) raise, which it will deploy in about a dozen companies located mainly in France. The fund took a little longer to close than originally planned but it is significantly larger than it had originally intended. “Our initial objective was €200 million,” Truffle Capital CEO and co-founder Philippe Pouletty told BioWorld.
BEIJING – Questionable data found in research papers supervised by renowned Chinese immunologist Cao Xuetao have caused a stir in the life sciences community, shaking the reputation of an internationally prominent figure in the field of immunology.
BEIJING – Questionable data found in research papers supervised by renowned Chinese immunologist Cao Xuetao have caused a stir in the life sciences community, shaking the reputation of an internationally prominent figure in the field of immunology.