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BioWorld - Saturday, July 18, 2026
Home » breast cancer

Articles Tagged with ''breast cancer''

Revtorpyk

Celcuity’s Revtorpyk wins FDA nod in breast cancer

July 15, 2026
By Jennifer Boggs
No Comments
For the second time in two months, Celcuity Inc. failed to generate investor excitement despite disclosing positive news, this time following the U.S. FDA approval of Revtorpyk (gedatolisib) in a subset of breast cancer patients, marking the firm’s first foray into the commercial space and introducing a new treatment option for patients. Wall Street instead focused on an unanticipated launch delay, sending shares of Celcuity (NASDAQ:CELC) down 17.6% to close July 15 at $91.51.
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Illustration of lymphocytes attacking cancer cell
Immuno-oncology

Coregen’s CRG-150 gains IND clearance for solid tumors

July 8, 2026
No Comments
Coregen Inc. has obtained IND clearance from the FDA for CRG-150, a novel adoptive cell therapy targeting SRC-3 (steroid receptor coactivator 3).
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Illustration of tumor in breast
Cancer

Astex Pharmaceuticals and Genentech collaborate in breast cancer

July 7, 2026
No Comments
Astex Pharmaceuticals Ltd. has entered into an exclusive, worldwide research collaboration and license agreement with Genentech Inc., a member of the Roche Group, to identify small-molecule drug candidates with selective inhibitory activity as potential treatments for breast cancer.
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Illustration of triple-negative breast cancer cells
Cancer

EVmiR-885-5p limits TNBC spread in preclinical models

June 22, 2026
No Comments
Researchers at Theramir Ltd. presented preclinical proof-of-concept data for a new extracellular vesicle (EV) platform engineered to deliver miR-885-5p (EVmiR885-5p), targeting leukocyte-specific protein-1 (LCP-1)-mediated cytoskeletal remodeling in triple-negative breast cancer (TNBC) models.
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3D dollar sign

Ona raises $86.6M series B for ADCs to treat advanced cancers

June 4, 2026
By Nuala Moran
No Comments
Antibody-drug conjugate (ADC) specialist Ona Therapeutics SL has closed an oversubscribed series B at $86.6 million, as clinical development of the lead program ONA-255 in advanced treatment-resistant breast cancer gathers steam.
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Dollar sign between hands

Mammogen raises $30M for blood-based breast cancer detection assay

June 3, 2026
By Shani Alexander
No Comments
Mammogen Inc. raised $30 million in equity financing in a series A round to support the clinical advancement and commercialization of its RNA-powered molecular diagnostics platform. The company’s lead product is Gentru-breast, a blood-based assay designed to detect molecular signatures associated with breast cancer from a simple blood draw.
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Breast cancer cell

ASCO 2026: Celcuity’s positive phase III gets no love from investors

June 2, 2026
By Brian Orelli
No Comments
Minneapolis-based Celcuity Inc. was like the Rolling Stones at the 2026 American Society of Clinical Oncology annual meeting. The company reported positive phase III data for its pan-PI3K/mTORC1/2 inhibitor gedatolisib, but Celcuity (NASDAQ:CELC) couldn’t get any satisfaction from investors who sent shares down 25.7%, or $31.54, to $91.42 on June 2, 2026.
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Microscope with laptop displaying histology image.
Immuno-oncology

FDA approves IND for Iovance’s TIL therapy IOV-5001

June 2, 2026
No Comments
Iovance Biotherapeutics Inc. has received IND clearance from the FDA for IOV-5001, a next-generation interleukin-12 (IL-12)-tethered tumor-infiltrating lymphocyte (TIL) therapy.
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Pink and orange test tubes
Cancer

Alaw nominates CDK4 inhibitor AL-433 as development candidate

June 1, 2026
No Comments
Alaw Therapeutics Inc. has announced the nomination of AL-433, a selective, brain-penetrant CDK4 inhibitor, as a development candidate.
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Art concept for oncolytic virus
Immuno-oncology

KLS-3021 suppresses tumors and induces immune memory in TNBC

May 27, 2026
No Comments
Kolon Life Science Inc. is developing KLS-3021, a next-generation oncolytic vaccinia virus designed to express the PH20, IL-12 and PD-1-Fc transgenes to mediate receptor-independent tumor cell killing and enhance antitumor immune responses.
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