Icecure Medical Ltd.’s Prosense system demonstrated a 100% success rate in destroying breast cancer tumors that were less than or equal to 25 millimeters, according to a study published in the British Journal of Radiology.
Researchers at Rockefeller University have identified a signaling loop between breast cancer cells and sensory neurons that promoted tumor metastasis, and showed that in animal models, treatment with the approved anti-nausea medication aprepitant could disrupt that loop.
For the first time in six years, the U.K.’s National Institute for Health and Care Excellence (NICE) is refusing to recommend a breast cancer treatment. It cited price as the issue.
Researchers from Northeast Normal University in Changchun demonstrated that compound AW-01178 reversed the abnormal regulation of E-cadherin by inhibiting the class I HDAC enzyme.
The first patenting to be published in the name of Wave View Imaging Inc. sees its co-founders file for additional protection of their imaging technology which can be used to monitor breast cancer treatment.
Researchers from Shuttle Pharmaceuticals LLC and Georgetown University have described the in vitro and in vivo profile of SP-1-303, designed as a dual-function histone deacetylase (HDAC) inhibitor and ataxia-telangiectasia mutated protein (ATM) activator, in breast cancer models.
Exelixis Inc. has disclosed membrane-associated tyrosine- and threonine-specific Cdc2-inhibitory kinase (PKMYT1) inhibitors reported to be useful for the treatment of cancer.
Breast cancer is the leading cancer malignancy in women and triple-negative breast cancer (TNBC) is among the most aggressive types as it is insensitive to endocrine and HER2-targeted therapy because it lacks all three hormonal receptors.
Previous studies have demonstrated that the natural product isotoosendanin (ITSN) inhibited triple-negative breast cancer (TNBC) metastasis by preventing epithelial-mesenchymal transition (EMT) and lamellipodia formation regulated by the TGF-β–Smad2/3 signaling pathway in TNBC cells through directly binding to TGF-β receptor type 1 (TGF-βR1).
